Human pathology

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t(16;21)(p11;q22)

16p11 and 21q22

Target genes

- FUS at 16p11
- ERG at 21q22

Tumors

- ES/PNET tumors (Ewing tumors)

- de novo acute non lymphocytic leukemia (ANLL) (may be preceded by a myelodysplastic syndrome) (MDS)

- blast crisis of chronic myelogenous leukemia (CML) (one case)

P.S.


- AGCOH