Uterus

• tubal metaplasia of the endometrium
  17 January

  ciliated cell metaplasia of the endometrium
  Definition: Tubal metaplasia of the endometrium refers to the presence of large number of tubal-type ciliated cells in the endometrial mucosa. It is usually an incidental finding but is seen more commonly in association with endometrial hyperplasia. It may result in abnormal cells in a Pap smear. It is not a risk factor for endometrial adenocarcinoma.
  Images
  http://www.webpathology.com/image.asp?case=563&n=1
  Tubal metaplasia in PAP smear (...)

• endometrial epithelial anomalies
  17 January

  Examples
  metaplasia of the endometrium
  endometrial atrophy
  endometrial hyperplasia
  endometrial dysplasia
  Evaluation of endometrium (Sternberg approach)
  Reference : Mills, SE: Sternberg’s Diagnostic Surgical Pathology (4th Ed); Lippincott Williams & Wilkins, 2004
  Based on low power microscopic appearance
  Pattern 1: proliferations composed of glands and supportive non-neoplastic endometrial stroma ; must evaluate gland to stroma ratio , glandular and stromal features , (...)

• metaplasia of the endometrium
  17 January

  Types
  tubal metaplasia of the endometrium
  oncocytic metaplasia of the endometrium / eosinophilic metaplasia
  mucinous metaplasia of the endometrium
  See also
  endometrial anomalies

• endometrial papillary metaplasia
  13 January

  papillary metaplasia on the endometrial surface epithelium
  Definition: Histopathology of patients with dysfunctional uterine bleeding due to an anovulatory cycle usually contain endometrial glandular and stromal breakdown (EGBD) and papillary metaplasia on the endometrial surface epithelium, if an appropriate sample has been collected.
  The appearance of MCIP with condensed stromal clusters originated from the papillary metaplasia, which occurred on the endometrial surface epithelium. The (...)

• endometrial glandular and stromal breakdown
  13 January

  EGBD
  Definition: Histopathology of patients with dysfunctional uterine bleeding due to an anovulatory cycle usually contain endometrial glandular and stromal breakdown (EGBD) and papillary metaplasia on the endometrial surface epithelium, if an appropriate sample has been collected.
  The appearance of MCIP with condensed stromal clusters originated from the papillary metaplasia, which occurred on the endometrial surface epithelium. The cytologic observation of those cells may be a useful (...)

• low-grade endometrial stromal sarcoma
  10 January

  low-grade ESS; LGESS; LG-ESS
  Low grade endometrial stromal sarcoma has a monotonous population of ovoid cells, frequent arterioles, and is positive for beta-catenin, CD10, ER and PR.
  Images
  low-grade endometrial stromal sarcoma https://twitter.com/A_Elshaikh/status/817565805332361218 https://twitter.com/UABPathology/status/825383992488755200
  See also
  endometrial stromal sarcoma (...)

• endometrial cellular infiltration
  5 January

  Types endometrial neutrophilic infiltration endometrial eosinophilic infiltration endometrial lymphocytic infiltration endometrial plasmacytic infiltration endometrial histiocytic infiltration

• serous endometrial intraepithelial carcinoma
  7 December 2016

  serous endometrial intraepithelial carcinoma (SEIC)
  Uterine serous endometrial intraepithelial carcinoma (SEIC) is an immediate precursor of invasive carcinoma.
  The majority of stage IA SEICs are curable, but those with latent peritoneal metastasis and/or capillary lymphatics invasion may have poor prognoses.
  Careful pathologic staging is thus needed to predict the risk of recurrence and to determine postoperative therapeutic strategies.
  Although SEICs confined to the uterine (...)

• high-grade endometrial stromal sarcoma
  1 November 2016

  See also
  endometrial stromal sarcoma (ESS)
  Molecular biology
  JAZF1-JJAZ1 fusion gene fusion genes between JAZF1 at 7p15 and JJAZ1 at 17q21 by t(7;17)(p15;q21) (#12850374#, #11371647#)
  NUTM2-YWHAE fusion gene in high-grade endometrial stromal sarcoma (YWHAE-NUTM2 )
  BCOR-ZC3H7B fusion gene in high-grade endometrial stromal sarcoma (ZC3H7B-BCOR ) (#27631520#)

• endometrial stromal tumors
  1 November 2016

  Tumors
  benign endometrial stromal tumor
  endometrial stromal sarcoma (malignant endometrial stromal tumor )
  IHC
  CD10 in endometrial stromal tumors (ESTs) / endometrial stromal sarcoma (ESS) / endometrial stromal nodule (ESN)
  CD10 have a positive staining in a small number of endometrial stromal sarcomas as well as in normal endometrial stroma.
  CD10 is a reliable and sensitive immunohistochemical marker of normal endometrial stroma.
  Positivity, which is often strong and/or (...)

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