Uterus

• endometrial intraepithelial carcinoma
  11 May 2017

  Endometrial intraepithelial carcinoma (EIC)
  Definition: Endometrial intraepithelial carcinoma (EIC) is non-invasive, morphologically the same as serous carcinoma, and positive for p53 and stains strongly for Ki-67.
  EIC is a precursor of serous carcinoma.
  IHC
  Endometrioid intraepithelial carcinoma (EIC) is positive for p53 and Ki-67.
  See also
  precursor anomaly / precursor lesion
  uterine serous (...)

• atypical polypoid adenomyoma
  10 May 2017

  Atypical polypoid adenomyoma is biphasic: it has a stroma composed of fascicles of smooth muscle, and numerous atypical epithelial glands that have architecturally lost polarity but are not pleomorphic, as seen here. There are minimal mitotic figures, and squamous metaplasia is frequently found.
  Atypical polypoid adenomyoma is composed of 1) fascicles of smooth muscle, 2) atypical epithelial glands, and (frequently) 3) squamous (...)

• uterine spindle cell tumors
  9 May 2017

  Differential diagnosis
  endometrial stromal tumors (ESTs) endometrial stromal tumors may pose diagnostic challenges particularly when they exhibit variant histologic appearances, involve extrauterine sites, or present as metastatic disease. In such cases, use of immunohistochemical markers and identification of specific nonrandom chromosomal rearrangements may be helpful. endometrial stromal nodule (ESN): Stromal nodule does not have atypical mitoses, and has a lower number of mitosis. (...)

• uterine endometrioid adenocarcinoma
  11 April 2017

  uterine endometrioid carcinoma PO WP
  Definition: Endometrioid adenocarcinoma hasinvasive nests and sheets of endometrioid glands with cribriforming. Endometrioid adenocarcinoma is positive for vimentin, ER and PR.
  Images
  uterine endometrioid adenocarcinoma / uterine endometrioid carcinoma https://twitter.com/RikiSotillo/status/851332977367953412
  http://www.webpathology.com/image.asp?case=569&n=3
  Types
  well-differentiated endometrioid (...)

• uterine shedding
  2 April 2017

  Synopsis
  Also known as glandular and stroma breakdown
  Common in perimenopausal women
  condensation of endometrial stroma under surface endometrium and nuclear dust;
  associated with predecidualized stroma and glandular exhaustion;
  cannot assess architectural changes;
  may see signet ring cells (benign) if prolonged shedding
  Differential diagnosis
  uterine small cell (...)

• uterine endosalpingiosis
  2 April 2017

  PO
  See also
  endosalpingiosis nodal endosalpingiosis

• endosalpingiosis
  2 April 2017

  Localization
  uterine endosalpingiosis
  nodal endosalpingiosis

• endometrial metaplasia
  2 April 2017

  |PO|
  Definition :
  Endometrial metaplasia is opften due to hormonal or irritative stimuli (J Clin Pathol 2011;64:97, Am J Surg Pathol 1980;4:525).
  Endometrial metaplasia must be evaluated separately from hyperplasia
  Endometrial metaplasia tends to be associated with adenocarcinoma and is more common in women at high risk for endometrial carcinoma.
  Types
  endometrial clear cell metaplasia
  endometrial eosinophilic metaplasia / oxyphilic metaplasia
  endometrial intestinal metaplasia (...)

• dyssynchronous endometrium
  2 April 2017

  |PO|
  Weakly proliferative endometrium: Normal in prepubertal girls, perimenopausal or menopausal women Proliferative glands (columnar or cuboidal epithelium with pseudostratification, elongated and densely basophilic nuclei), but relatively reduced number of mitotic figures Glands usually tubular or cystic, may be closely packed Stroma also appears inactive with variable collagenization and minimal mitotic activity
  See also
  endometrial epithelial (...)

• endometrial anomalies
  2 April 2017

  Localization
  endometrial epithelial anomalies
  endometrial stromal anomalies
  endometriosis
  See also
  uterine anomalies

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