Uterus

• proliferative endometrium
  12 November

  Subtypes
  proliferative endometrium
  See also
  proliferative mucosa
  disordered mucosa

• endometrial simple atrophy
  11 November

  See also
  endometrial atrophy

• endometrial stroma
  11 November

  See also
  endometrium endometrial epithelium

• endometrial epithelium
  11 November

  Appearance
  cuboidal endometrial epithelium
  columnar endometrial epithelium
  Localization
  endometrial surface epithelium
  endometrial glands / endometrial glandular epithelium
  See also
  endometrium endometrial stroma

• endometrial anomalies
  11 November

  Examples
  endometrial atrophy
  endometrial hyperplasia
  endometrial dysplasia
  endometrial inflammation
  endometrial polyp
  endometrial tumors
  See also
  endometrium

• COL1A1-PDGFB-associated uterine fibrosarcoma
  8 November

  COL1A1-PDGFB fusion
  NTRK-rearranged uterine fibrosarcoma
  References
  The histologic spectrum of soft tissue spindle cell tumors with NTRK3 gene rearrangements. Suurmeijer AJ, Dickson BC, Swanson D, Zhang L, Sung YS, Huang HY, Fletcher CD, Antonescu CR. Genes Chromosomes Cancer. 2019 Nov;58(11):739-746. doi:10.1002/gcc.22767. PMID: #31112350#
  Uterine and vaginal sarcomas resembling fibrosarcoma: a clinicopathological and molecular analysis of 13 cases showing common NTRK-rearrangements (...)

• NTRK-rearranged uterine fibrosarcoma
  8 November

  NTRK-rearranged uterine fibrosarcoma
  References
  The histologic spectrum of soft tissue spindle cell tumors with NTRK3 gene rearrangements. Suurmeijer AJ, Dickson BC, Swanson D, Zhang L, Sung YS, Huang HY, Fletcher CD, Antonescu CR. Genes Chromosomes Cancer. 2019 Nov;58(11):739-746. doi:10.1002/gcc.22767. PMID: #31112350#
  Croce S, Hostein I, Longacre TA, Mills AM, Pérot G, Devouassoux-Shisheboran M, Velasco V, Floquet A, Guyon F, Chakiba C, Querleu D, Khalifa E, Mayeur L, Rebier F, (...)

• atypical endometrial hyperplasia
  4 November

  Endometrioid intraepithelial neoplasia (EIN) / Atypical endometrial hyperplasia PO

• uterine mesenchymal tumors
  10 July

  Uterine mesenchymal tumors are genetically heterogenous; those with uniform cytomorphology, best exemplified by endometrial stromal tumors, often contain various fusion genes.
  Novel fusions involving ESR1 and GREB1 , key factors in sex hormone pathways, have been implicated in rare uterine mesenchymal tumors.
  Particularly, the fusions between 5’-ESR1/GREB1 and 3’-NCOA2/NCOA3 were recently identified in 4 uterine tumors resembling ovarian sex-cord tumor (...)

• GREB1-rearranged uterine sarcomas with variable sex-cord differentiation
  10 July

  Pathology
  GREB1-rearranged uterine sarcomas with variable sex-cord differentiation. Growth regulation by estrogen in breast cancer 1 / GREB1 is a protein that in humans is encoded by the GREB1 gene. This gene is an estrogen-responsive gene that is an early response gene in the estrogen receptor-regulated pathway. It is thought to play an important role in hormone-responsive tissues and cancer. Three alternatively spliced transcript variants encoding distinct isoforms have been found for (...)

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