prostate malakoplakia
Synopsis
May involve prostate, usually associated with bladder disease
Ages 47+
Represents a peculiar form of tissue reaction to bacterial infection
Usually periductal, may resemble carcinoma on ultrasound, may actually coexist with carcinoma
Prostate enlarged on clinical examination
The prostatic glands are replaced by sheets of histiocytes, lymphocytes, and plasma cells.
Targetoid Michelis-Gutmann bodies are seen.
Differential diagnosis
nodular (...)
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Prostate
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prostatic malakoplakia
22 January 2012 -
prostatic eosinophilic infiltration
22 January 2012Prostatitis with eosinophils; prostatic eosinophilic infiltrate
Prostatitis with eosinophils
Differential diagnosis
nonspecific granulomatous prostatitis
eosinophilic prostatitis
iatrogenic granulomas
parasitic infestation -
prostatic intraepithelial neoplasia
21 January 2012prostate intraepithelial neoplasia; PIN WebPathology
Definition: Prostatic intraepithelial neoplasia (PIN) is a neoplastic transformation of the lining epithelium of prostatic ducts and acini. By definition, this process is confined within the epithelium therefore, intraepithelial.
Prostatic intraepithelial neoplasia (PIN) is a dysplasia of the epithelium lining prostate glands and is a probable precursor of prostatic carcinoma. The appearance of PIN may precede carcinoma by 10 or (...) -
prostatic atypical adenomatous hyperplasia
21 January 2012Atypical Adenomatous Hyperplasia; prostate atypical adenomatous hyperplasia
Atypical adenomatous hyperplasia (AAH) is a term that has been utilized to describe changes histologically seen in prostatic glands in the apex, periurethral region, and/or transition zone of the prostate.
AAH is a localized proliferation of small acini within the prostate. Such proliferations may be confused with carcinoma, but the glands with AAH still have a fragmented basal layer.
AAH can be difficult to (...) -
prostate adenomatous hyperplasia
21 January 2012Prostatic Hyperplasia; Nodular prostatic hyperplasia (also termed benign prostatic hyperplasia, or BPH);
Nodular prostatic hyperplasia (also termed benign prostatic hyperplasia, or BPH) is a common condition as men age.
Perhaps a fourth of men have some degree of hyperplasia by the fifth decade of life.
By the eighth decade, over 90% of males will have prostatic hyperplasia. However, in only a minority of cases (about 10%) will this hyperplasia be symptomatic and severe enough to require (...) -
chronic prostatitis
21 January 2012Chronic prostatitis may follow acute prostatitis, but is more likely to occur without prior history in older men, and may suggest an underlying obstructive urinary tract abnormality. There can be intermittent urinary frequency and dysuria. The prostate may not be enlarged. Prostatic massage may increase the yield of urine culture. Routine cultures, however, do not identify one common organism: Ureaplasma urealyticum.
Chronic abacterial prostatitis is the most common cause for prostatitis, (...) -
prostatitis
21 January 2012Synopsis
Diagnosis based on quantitative bacterial cultures and microscopic examination of fractionated urine specimens (first 10 ml of urine is urethral, midstream urine is from bladder) and expressed prostatic secretions
Definition: >10 WBC/HPF in prostatic secretions without pyuria; prostatic secretion cultures should have bacterial counts 10x urethral/bladder cultures
Clinical: elevated PSA
Treatment: difficult because antibiotics penetrate poorly into prostate
Micro: (...) -
acute prostatitis
21 January 2012Acute prostatitis is not common, but is most likely to occur in young men.
Causative agents include bacterial organisms similar to those causing urinary tract infections, as well as Neisseria gonorrheae.
A related complication of prostatic abscess is uncommon.
The edema and slight enlargement of the prostate with acute inflammation may cause acute rectal, lower back, or perineal pain along with fever. There can be dysuria. The prostate is enlarged and tender.
Urine culture may be done, (...) -
prostate pathology
21 January 2012Slideshows Prostate Pathology View more presentations from MCG Urology
Links
Prostate pathology on wepathology.com
WePath - Prostate
References
Immunohistochemical pitfalls in prostate pathology. Brimo F, Epstein JI. Hum Pathol. 2012 Mar;43(3):313-24. PMID: #22325142# -
prostate cancer-associated stroma
1 January 2012prostate adenocarcinoma-associated stroma
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