Blood and immunity

• mast cells
  29 December 2018

  mastocyte WKP
  Definition : A mast cell (also known as a mastocyte or formerly a labrocyte) is a type of white blood cell. Specifically, it is a type of granulocyte derived from the myeloid stem cell that is a part of the immune and neuroimmune systems and contains many granules rich in histamine and heparin.
  Although best known for their role in allergy and anaphylaxis, mast cells play an important protective role as well, being intimately involved in wound healing, angiogenesis, (...)

• immunology
  29 December 2018

  WKP
  Definition : Immunology is a branch of biology, that covers the study of immune systems in all organisms.
  Immunology charts, measures, and contextualizes the: physiological functioning of the immune system in states of both health and diseases.
  Pathology
  Malfunctions of the immune system in immunological disorders / immune diseases (such as autoimmune diseases , hypersensitivities , immune deficiencies , and transplant rejection.
  The physical, chemical and physiological (...)

• non-self
  29 December 2018

  WKP
  The distinction of self from non-self is a central concept in immunology.

• self
  29 December 2018

  WKP
  See also
  non-self
  self-non-self model
  Paywall references
  Transplantation and identity: a dangerous split? Carosella ED, Pradeu T. Lancet. 2006 Jul 15;368(9531):183-4. PMID: #16844470#

• self-non-self model
  29 December 2018

  https://en.wikipedia.org/wiki/Self
  The self-non-self theory has dominated immunology since the 1950s.
  See also
  self
  non-self
  Open references
  The danger theory: 20 years later. Pradeu T, Cooper EL. Front Immunol. 2012 Sep 17;3:287. doi:10.3389/fimmu.2012.00287. eCollection 2012. PMID: 23060876

• immunosenescence
  29 December 2018

  WKP
  Definition : Immunosenescence refers to the gradual deterioration of the immune system brought on by natural age advancement. It involves both the host’s capacity to respond to infections and the development of long-term immune memory, especially by vaccination.
  This age-associated immune deficiency is ubiquitous and found in both long- and short-living species as a function of their age relative to life expectancy rather than chronological time.
  It is considered a major (...)

• danger theory
  29 December 2018

  The self-non-self theory has dominated immunology since the 1950s. In the 1990s, Matzinger and her colleagues suggested a new, competing theory, called the "danger theory."
  Authors assess the danger theory vis-à-vis recent experimental data on innate immunity, transplantation, cancers and tolerance to foreign entities, and try to elucidate more clearly whether danger is well defined.
  Open references
  The danger theory: 20 years later. Pradeu T, Cooper EL. Front Immunol. 2012 Sep 17;3:287. (...)

• immunological memory
  29 December 2018

  Paywall references
  Immunological memory: What’s in a name? Pradeu T, Du Pasquier L. Immunol Rev. 2018 May;283(1):7-20. doi:10.1111/imr.12652. PMID: #29664563#

• PFAPA
  1 July 2017

  Periodic Fever Aphtous stomatitis Pharyngitis Adenitis; Mashall syndrome WKP
  Definition : The periodic fever , aphthous stomatitis , pharyngitis and adenitis or periodic fever aphthous pharyngitis and cervical adenopathy (PFAPA) syndrome is a medical condition, typically starting in young children, in which high fever occurs periodically at intervals of about 3–5 weeks, frequently accompanied by aphthous-like ulcers, pharyngitis and/or cervical adenitis (cervical lymphadenopathy). The (...)

• large lymphoid cells
  11 April 2017

  Images
  https://twitter.com/GeronimoJrLapac/status/851380384159989760
  Types
  large lymphoid cells large non-cleaved lymphocyte / centroblasts / centroblastic cells immunoblasts anaplastic lymphoid cells plasmablastic cells
  See also
  lymphoid cells small lymphoid cells

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