Blood and immunity

• immunological memory
  29 December 2018

  Paywall references
  Immunological memory: What’s in a name? Pradeu T, Du Pasquier L. Immunol Rev. 2018 May;283(1):7-20. doi:10.1111/imr.12652. PMID: #29664563#

• PFAPA
  1 July 2017

  Periodic Fever Aphtous stomatitis Pharyngitis Adenitis; Mashall syndrome WKP
  Definition : The periodic fever , aphthous stomatitis , pharyngitis and adenitis or periodic fever aphthous pharyngitis and cervical adenopathy (PFAPA) syndrome is a medical condition, typically starting in young children, in which high fever occurs periodically at intervals of about 3–5 weeks, frequently accompanied by aphthous-like ulcers, pharyngitis and/or cervical adenitis (cervical lymphadenopathy). The (...)

• large lymphoid cells
  11 April 2017

  Images
  https://twitter.com/GeronimoJrLapac/status/851380384159989760
  Types
  large lymphoid cells large non-cleaved lymphocyte / centroblasts / centroblastic cells immunoblasts anaplastic lymphoid cells plasmablastic cells
  See also
  lymphoid cells small lymphoid cells

• TRAPS
  27 March 2017

  TNF receptor-associated periodic syndrome, familial hibernian fever, TNF Receptor Associated Periodic Fever
  TNF Receptor Associated Periodic Fever (TRAPS), formerly known as Familial Hibernian fever, results from a defective gene on chromosome 12p that encodes the cellular membrane receptor protein for TNF (TNFRSF1A).
  Most of the 46 known mutations are at the extracellular portion of the protein.
  One proposed mechanism for TRAPS-associated inflammation is sustained TNF stimulation of (...)

• JAK2-mutated myeloproliferative disease
  8 March 2017

  See also
  JAK2-negative myeloproliferative disease
  Open references
  Two routes to leukemic transformation after a JAK2 mutation-positive myeloproliferative neoplasm. Beer PA, Delhommeau F, LeCouédic JP, Dawson MA, Chen E, Bareford D, Kusec R, McMullin MF, Harrison CN, Vannucchi AM, Vainchenker W, Green AR. Blood. 2010 Apr 8;115(14):2891-900. doi:10.1182/blood-2009-08-236596. PMID: (...)

• lymphoid cells
  23 January 2017

  Morphological types
  small lymphoid cells small round lymphoid cell - mature lymphocytes small cleaved lymphoid cell - centrocytes small round plasmacytoid cell - immunocytes monocytoid small lymphoid cell - monocytoid lymphocytes
  intermediate lymphoid cells convoluted lymphoblast - lymphoblasts small non-cleaved lymphocyte / Burkitt lymphoblasts
  large lymphoid cells large non-cleaved lymphocyte / centroblasts / centroblastic cells immunoblasts anaplastic lymphoid cells (...)

• B-cell acute lymphoblastic leukemia
  17 January 2017

  B-cell ALL
  Molecualr biology
  AFF1-MLL gene fusion
  ETV6-RUNX1 gene fusion
  BCR-ABL1 gene fusion
  See also
  acute lymphoblastic leukemia ALL

• centroblasts
  6 January 2017

  Images
  immunoblasts vs centroblasts https://twitter.com/KyleBradleyMD/status/799714229842419712

• immunoblasts
  6 January 2017

  immunoblast. Adj. immunoblastic
  Images
  immunoblasts vs centroblasts https://twitter.com/KyleBradleyMD/status/799714229842419712

• myeloma cells
  5 January 2017

  Images
  plasma cell myeloma with numerous cytoplasmic granules https://twitter.com/feldstej/status/703642895602098176
  myeloma cells in bone marrow cytology https://twitter.com/chriscogbillmd/status/712786667187245057

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