Diagnostic antibodies

• myoepithelial cell markers
  2 April

  Types
  p63
  SMA / smooth muscle actin
  See also
  immunohistochemical markers

• GCDFP
  2 April

  Gross cystic disease fluid protein 15 (GCDFP-15) PO

• CK903
  2 April

  Cytokeratin 34 beta E12 PO1 PO2
  See also
  CKs / cytokeratins

• HMWCKs
  2 April

  HMWCK ; high molecular weight cytokeratins
  Examples
  CK903 / Cytokeratin 34 beta E12
  CK5/6

• Cam5.2
  2 April

  Cam5.2 is a diagnostic antibody against low molecular weight cytokeratins (LMWCKs ).

• LMWCKs
  2 April

  low molecular weight cytokeratins
  Examples
  Cam5.2

• p40
  22 February

  p40

• BerEP4
  20 January

  Definition: BerEP4 : monoclonal antibody againt EPCAM
  Images
  membranous BerEp4 expression in normal apocrine glands. https://twitter.com/JMGardnerMD/status/847448839556546563
  Open references
  Use of Ber-EP4 and Epithelial Specific Antigen to Differentiate Clinical Simulators of Basal Cell Carcinoma.
  Dasgeb B, Mohammadi TM, Mehregan DR.
  Biomark Cancer. 2013 Jun 25;5:7-11. doi:10.4137/BIC.S11856.
  PMID: #24179394#
  The immunohistochemical differential diagnosis of microcystic (...)

• SP142
  31 October 2016

  Ventana Roche SP142 PD-L1 antibodies
  Open references
  Expression of PD-L1 in triple-negative breast cancer based on different immunohistochemical antibodies. Sun WY, Lee YK, Koo JS. J Transl Med. 2016 Jun 10;14(1):173. doi:10.1186/s12967-016-0925-6. PMID: #27286842# (Free)
  Disseminated histiocytoses biomarkers beyond BRAFV600E: frequent expression of PD-L1. Gatalica Z, Bilalovic N, Palazzo JP, Bender RP, Swensen J, Millis SZ, Vranic S, Von Hoff D, Arceci RJ. Oncotarget. 2015 Aug (...)

• mASH1
  27 September 2016

  Diagnostic use
  mASH1 is Highly Specific for neuroendocrine carcinomas : An Immunohistochemical Evaluation on Normal and Various Neoplastic Tissues. http://dx.doi.org/10.5858/arpa.2015-0489-OA

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