Skin

• eosinophilic skin diseases
  13 March

  eosinophilic dermatoses
  Definition: Eosinophilic skin diseases, commonly termed as eosinophilic dermatoses, refer to a broad spectrum of skin diseases characterized by eosinophil infiltration and/or degranulation in skin lesions, with or without blood eosinophilia.
  The majority of eosinophilic dermatoses lie in the allergy-related group, including allergic drug eruption, urticaria, allergic contact dermatitis, atopic dermatitis, and eczema.
  Parasitic infestations, arthropod bites, and (...)

• multiple nevi lipomatosis cutaneous superficialis
  3 March

  Hamartome lipomateux superficiel de Hoffmann-Zurhelle; Nevus lipomatosis cutaneous superficialis of Hoffmann-Zurhelle; multiple nevi lipomatosis cutaneous superficialis of Hoffmann-Zurhelle
  Nevus lipomatosus cutaneous superficialis (NLCS) is a rare hamartomatous skin lesion histologically characterised by the presence of mature fat tissue within the dermis.
  Clinically, two types of NLCS can be distinguished:
  a multiple type of Hoffmann-Zurhelle
  a solitary type.
  Histologically, the (...)

• eyeliner sign
  27 December 2017

  Definition: “Eyeliner sign” is seen in squamous cell carcinoma in situ. Atypical keratinocytes fill epidermis but spare basal layer (line of normal basal keratinocytes under the atypical ones resembles eyeliner 👁).
  Melanoma in situ does not have this pattern.
  Images
  “Eyeliner sign” is seen in squamous cell carcinoma in situ. https://twitter.com/JMGardnerMD/status/945671045452836870

• hidradenitis
  18 July 2017

  Images
  Hidradenitis suppurativa. Sinus tract opens to the surface, inflamed granulation tissue, mixed inflammation with abscess formation, scarring.
  Examples
  hidradenitis suppurativa

• lichen planus pemphigoides
  6 July 2017

  Images
  lichen planus (clinically and histologically) + bullous pemphigoides = lichen planus pemphigoides : extensive subepidermal clefting and eosinophils are a clue to diagnosis. https://twitter.com/DrZembowicz/status/882695037225762816

• cutaneous pleomorphic spindle cell tumors
  4 July 2017

  pleomorphic spindle cell skin tumors; pleomorphic spindle cell tumors of the skin
  Videos
  atypical fibroxanthoma (AFX) vs other cutaneous pleomorphic spindle cell tumors https://youtu.be/zdWFmSoouXM

• hypertrophic lichen sclerosus
  28 June 2017

  Images
  Hypertrophic lichen sclerosus https://twitter.com/LinskeyKaty/status/879496539785318400
  See also
  lichen sclerosus

• sclerodermoid GVHD
  25 June 2017

  Images
  Sclerodermoid GVHD https://twitter.com/FungMaxwell/status/878492468487929858 https://twitter.com/FungMaxwell/status/878491601475035136
  See also
  GVH / GVHD
  sclerodermoid anomalies

• cutaneous myxoma
  21 June 2017

  superficial angiomyxoma WKP
  Definition: A cutaneous myxoma, a.k.a. superficial angiomyxoma, consists of a multilobulated myxoid mass containing stellate or spindled fibroblasts with pools of mucin forming cleft-like spaces. There is often a proliferation of blood vessels and an inflammatory infiltrate.
  Immunostaining is positive for vimentin, negative for cytokeratin and desmin, and variable for CD34, Factor VIIIa, SMA, MSA and S-100.
  Clinically, it may present as solitary or (...)

• basal cell carcinoma with reticulated pattern
  20 June 2017

  Images
  basal cell carcinoma with reticulated pattern https://twitter.com/JMGardnerMD/status/876979193552220164
  See also
  basal cell carcinoma
  reticulated pattern

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