Skin

• large clear cells in the epidermis
  10 September

  Single cells or clusters of cells spread throughout the epidermis
  Etiology
  mammary Paget disease
  See also
  epidermal anomalies

• interface reaction pattern
  3 September

  Paywall references
  https://pubmed.ncbi.nlm.nih.gov/31278974/
  https://www.sciencedirect.com/science/article/abs/pii/S0046817719301121

• acute eczematous dermatitis
  3 September

  PO
  Synopsis
  spongiosis
  perivascular lymphocytic infiltrate
  superficial dermal edema
  Differential diagnosis
  drug reaction: prominent eosinophilic infiltrate

• tinea versicolor
  3 September

  PO
  Definition : Infection by Malassezia furfur, often of upper trunk.
  Synopsis
  Variably pigmented macules of all sizes,
  orthokeratotic hyperkeratosis
  yeast spores and pseudohyphae within stratum corneum
  Short hyphae and spores (spaghetti and meatballs) with GMS or PAS stains
  Differential diagnosis
  presence of fungi does not rule out coexisting inflammatory and neoplastic (...)

• molluscum contagiosum
  3 September

  Images
  https://twitter.com/JMGardnerMD/status/1433399819775655936
  See also
  viral inclusions

• Miescher radial granuloma
  16 August

  Miescher radial granuloma: characteristic finding of erythema nodosum septal collection of histiocytes surrounding a cleft (appear to look like spaces); reported in Sweet syndrome, nodular vasculitis and necrobiotic lipodica

• erythema nodosum
  16 August

  WKP PO
  Synopsis
  A prototype of septal panniculitis, characterized by vascular changes, septal inflammation, hemorrhage and variable acute and chronic panniculitis
  Both septal and lobular panniculitis
  Marked septal fibrosis, infiltrated by lymphocytes, neutrophils, histiocytes and granulomas with giant cells
  Septal infiltrate spills over to affect the fat lobules
  Dermis shows perivascular and periadnexal chronic inflammatory cell infiltrate
  Early, the septal inflammation is (...)

• stasis dermatitis
  16 August

  WKP PO
  Synopsis
  Characterstic lobular pattern of superficial and deep dermal neovascularization
  dermal fibrosis
  perivascular lymphocytic infiltrates
  histiocytes and variable number of plasma cells
  extravasated erythrocytes
  hemosiderin laden macrophages
  hyperplasia of endothelial cells
  variable acanthosis and hyperkeratosis
  See also
  dermatitis

• lymphocytic infiltrate of Jessner
  16 August

  Jessner lymphocytic infiltration of skin PO
  Synopsis
  Variant of tumid lupus erythematosus
  Erythematous annular plaques that heal without scarring or dyspigmentation
  Superficial and deep perivascular and periadnexal lymphocytic infiltrate with plasma cells
  Absence of epidermal changes and mucin in dermis is differentiating feature from discoid lupus erythematosus

• lupus panniculitis
  16 August

  Synopsis
  lymphocytes, plasma cells, neutrophils with karyorrhectic debris and rare eosinophils in subcutaneous fat lobules and septa
  hyaline fat necrosis
  See also
  cutaneous lupus erythematosus

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