desmoplastic small round cell tumor
Wednesday 26 November 2003
Desmoplastic small round cell tumor (DSRCT) is a rare, aggressive, malignant tumor usually present with widespread abdominal serosal involvement. Isolated cases occur in limbs, head and neck, and brain.
t(11;22)(p13;q12) reciprocal translocation
Epithelial and mesenchymal markers were coexpressed in the tumor cells.
WT1 expression (10843285)
EWS/WT1 fusion transcript (8604806)
small blue round cell tumors
Barnoud R, Sabourin JC, Pasquier D, Ranchere D, Bailly C, Terrier-Lacombe MJ, Pasquier B. Immunohistochemical expression of WT1 by desmoplastic small round cell tumor: a comparative study with other small round cell tumors. Am J Surg Pathol. 2000 Jun;24(6):830-6. PMID: 10843285