The Mammalian Phenotype (MP) Browser is under development as a community effort to provide standard terms for annotating phenotypic data. You can use this browser to view terms, definitions, and term relationships in a hierarchical display. Groups are actively using these terms for annotation now, and direct links between terms and annotated phenotypes will be available in future (...)
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Concept
Articles
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Mammalian Phenotype (MP) Browser
16 October 2003 -
anatomoclinical correlation
11 July 2003 -
autoimmunity
16 August 2004Acquisition by mammals of an adaptive immune system was an evolutionary leap, but occurred at the cost of autoimmunity.
The necessity for self-recognition was appreciated in 1900, but autoimmune disease did not become a clinical reality until the 1950s-still the perimeters are indistinct.
Autoimmune responses recapitulate the complex events of normal immune responses but cannot shut down.
Immune tolerance is established during repertoire development centrally in thymus or bone marrow by (...) -
transcriptional hierarchy
19 July 2003 -
self-organization
1 December 2003Self-organization concepts that were first developed in chemistry and physics and then applied to various morphogenetic problems in biology over the past century are now beginning to be applied to the organization of the living cell.
See also
self-assembly
Open references
Crowd behaviour during high-stress evacuations in an immersive virtual environment. Moussaïd M, Kapadia M, Thrash T, Sumner RW, Gross M, Helbing D, Hölscher C. J R Soc Interface. 2016 Sep;13(122). pii: 20160414. (...) -
microscopical lesions
7 January 2005histologic lesion
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macroscopical lesions
7 January 2005gross lesions, macroscopic lesions
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molecular time
1 May 2004References
Blair Hedges S, Kumar S. Precision of molecular time estimates. Trends Genet. 2004 May;20(5):242-7. PMID: #15109778#
Reisz RR, Muller J. Molecular timescales and the fossil record: a paleontological perspective. Trends Genet. 2004 May;20(5):237-41. PMID: #15109777# -
european haplogroup clusters
14 November 2003 -
linkage disequilibrium
23 November 2003Patterns of linkage disequilibrium (LD) reveal the action of evolutionary processes and provide crucial information for association mapping of disease genes.
A complete description of human genetic variation requires more than just properties of isolated genes, microsatellites or SNPs.
How these vary simultaneously within a part or whole chromosome requires statistics of correlation between the variation at different positions, and these are usually described by patterns of linkage (...)
