Cellular functions

Articles

• phagocytosis
  23 April 2004

  Definition: Phagocytosis is a specific form of endocytosis involving the vesicular internalization of solid particles, such as bacteria. It is therefore distinct from other forms of endocytosis such as pinocytosis, the vesicular internalization of various liquids, and recptor-dependent endocytosis.
  Phagocytosis (literally, cell-eating) is the process by which cells ingest large objects, such as cells which have undergone apoptosis, bacteria, or viruses. The membrane folds around the (...)

• cellular aging
  7 March 2004

  Cellular aging is the result of a progressive decline in the proliferative capacity and life span of cells and the effects of continuous exposure to exogenous influences that result in the progressive accumulation of cellular and molecular damage. Structural and Biochemical Changes with Cellular Aging
  A number of cell functions decline progressively with age.
  Oxidative phosphorylation by mitochondria is reduced, as is synthesis of nucleic acids and structural and enzymatic proteins, (...)

• protein transport
  20 October 2003

  protein trafficking, intracellular protein transport

• cellular invasion
  29 October 2003

  tumor cell invasion, cancer cell invasion

• transcytosis
  13 July 2003

  Function
  The apical and basolateral borders of epithelial cells are distinguished by their different protein and lipid components. The sorting of newly synthesized membrane constituents to the appropriate region of the cell is accomplished either in the trans-Golgi network or by transcytosis, the selected transport of proteins to the appropriate surface.
  Transcytosis is involved in the internalization of proteins and ligands at one surface and their transport to another.
  See also (...)

• cardiomyocyte apoptosis
  14 April 2004

  References
  Kang PM, Izumo S. Apoptosis in heart: basic mechanisms and implications in cardiovascular diseases. Trends Mol Med. 2003 Apr;9(4):177-82. PMID: #12727144#

• cell cycle
  13 July 2003

  cellular cycle

• mitosis
  13 July 2003

  Images
  in a glandular epithelium
  https://twitter.com/BeynonMD/status/740787261046919169
  in epidermis
  https://twitter.com/doctormisti/status/
  numerous atypical mitoses
  https://twitter.com/smlungpathguy/status/743442537763971073
  Final steps
  The final stages of mitosis begin in anaphase, when the mitotic spindle segregates the duplicated chromosomes. Mitotic exit is then completed by disassembly of the spindle and packaging of chromosomes into daughter nuclei.
  The successful (...)

• cell-cell adhesion
  14 March 2004

  Cell-cell adhesion involve transmembrane glycoproteins such as cell adhesion molecules and integrins, which are thought to function via interactions of their cytoplasmic domains with proteins associated with the cytoskeleton (as vinculin or talins).
  Cadherin-mediated cell-cell junctions
  The formation of cadherin-mediated cell-cell junctions is accompanied by a profound remodeling of the actin cytoskeleton.
  The Arp2/3 complex and its activator cortactin drive the assembly of branching (...)

• exocytosis
  2 December 2003

  exocytic transport

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