Cellular functions

Articles

• phagocytosis
  23 April 2004

  Definition: Phagocytosis is a specific form of endocytosis involving the vesicular internalization of solid particles, such as bacteria. It is therefore distinct from other forms of endocytosis such as pinocytosis, the vesicular internalization of various liquids, and recptor-dependent endocytosis.
  Phagocytosis (literally, cell-eating) is the process by which cells ingest large objects, such as cells which have undergone apoptosis, bacteria, or viruses. The membrane folds around the (...)

• chromatin remodeling
  29 October 2003

  chromatin remodelling, chromatin-remodeling

• cellular aging
  7 March 2004

  Cellular aging is the result of a progressive decline in the proliferative capacity and life span of cells and the effects of continuous exposure to exogenous influences that result in the progressive accumulation of cellular and molecular damage. Structural and Biochemical Changes with Cellular Aging
  A number of cell functions decline progressively with age.
  Oxidative phosphorylation by mitochondria is reduced, as is synthesis of nucleic acids and structural and enzymatic proteins, (...)

• cell cycle
  13 July 2003

  cellular cycle

• proteolysis
  19 July 2003

  Types
  ubiquitin-independent proteolysis
  ubiquitin-dependent proteolysis
  Pathology of proteolysis
  Anomalies of proteases genes (53 human diseases are caused by mutations in protease genes)
  nonsyndromic deafness (transmembrane serine protease TMPRSS3)
  early-onset familial Alzheimer’s disease (presenilin-1 PSEN1 and presenilin-2 PSEN2)
  pycnodysostosis (cathepsin-K CTSK) (MIM.265800)
  Papillon-Lefevre and Haim-Munk syndrome (MIM.245000)
  limb-girdle muscular dystrophy type 2A (...)

• protein trafficking
  3 November 2003

  Features
  secretory protein trafficking
  References
  Karcher RL, Deacon SW, Gelfand VI. Motor-cargo interactions : the key to transport specificity. Trends Cell Biol. 2002 Jan ;12(1):21-7. PMID : #11854006#

• neuronal migration
  20 November 2003

  anomalies of neuronal migration

• synaptic plasticity
  4 December 2003

  References
  Turrigiano GG. More than a sidekick: glia and homeostatic synaptic plasticity. Trends Mol Med. 2006 Oct;12(10):458-60. PMID: #16931159#
  Collingridge GL, Isaac JT, Wang YT. Receptor trafficking and synaptic plasticity. Nat Rev Neurosci. 2004 Dec;5(12):952-62. PMID: #15550950#
  Blitz DM, Foster KA, Regehr WG. Short-term synaptic plasticity: a comparison of two synapses. Nat Rev Neurosci. 2004 Aug;5(8):630-40. PMID: #15263893#
  Winder DG, Egli RE, Schramm NL, Matthews RT. (...)

• neuronal survival
  16 July 2003
• DNA repair
  13 July 2003

  DNA reparation, DNA damage response, gene repair

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