Cellular functions

Articles

• phagocytosis
  23 April 2004

  WKP
  Definition: Phagocytosis is a specific form of endocytosis involving the vesicular internalization of solid particles, such as bacteria. It is therefore distinct from other forms of endocytosis such as pinocytosis, the vesicular internalization of various liquids, and recptor-dependent endocytosis.
  Phagocytosis involves three distinct but interrelated steps:
  (1) recognition and attachment of the particle to be ingested by the leukocyte;
  (2) its engulfment, with subsequent (...)

• chromosome positioning
  27 November 2003

  References
  Parada LA, Roix JJ, Misteli T. An uncertainty principle in chromosome positioning. Trends Cell Biol. 2003 Aug;13(8):393-6. PMID: #12888289#
  Parada L, Misteli T. Chromosome positioning in the interphase nucleus. Trends Cell Biol. 2002 Sep;12(9):425-32. PMID: #12220863#

• mitoses
  13 July 2003

  mitosis
  Images
  in a glandular epithelium
  https://twitter.com/BeynonMD/status/740787261046919169
  in epidermis
  https://twitter.com/doctormisti/status/
  numerous atypical mitoses
  https://twitter.com/smlungpathguy/status/743442537763971073
  Pathology
  abnormal mitosis / abnormal mitoses
  quantitative variations
  no mitosis
  increased mitoses
  low mitotic activity / inconspicuous mitoses
  moderate mitotic activity / frequent mitoses
  high mitotic activity / numerous mitoses (...)

• neuronal survival
  16 July 2003
• DNA repair
  13 July 2003

  DNA reparation, DNA damage response, gene repair

• extracellular matrix remodeling
  11 July 2003

  References
  Stamenkovic I. Extracellular matrix remodelling: the role of matrix metalloproteinases. J Pathol. 2003 Jul;200(4):448-64. PMID: #12845612#

• cellular interactions
  10 July 2003

  Types
  immune-cell interactions
  Pathology of cellular interactions
  References
  Friedl P, Storim J. Diversity in immune-cell interactions: states and functions of the immunological synapse. Trends Cell Biol. 2004 Oct;14(10):557-67. PMID: #15450978#

• Schwann cells myelination
  25 June 2003

  Anomalies:

• cardiomyocytic regeneration
  27 February 2007

  cardiomyocyte regeneration, myocyte renewal

• genomic stability
  13 July 2003

  A fundamental axiom of genetic inheritance is a requirement for exceptional genetic stability over many generations of cells and organisms. However, cells have to contend with both intracellular and extracellular environments that constantly challenge the chemical stability of the genome.
  Additionally, although normal metabolic transactions of DNA such as replication, recombination and repair are generally highly accurate, there are limits to the fidelity of these processes, so genomic (...)

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