Cellular functions

Articles

• cellular aging
  7 March 2004

  Cellular aging is the result of a progressive decline in the proliferative capacity and life span of cells and the effects of continuous exposure to exogenous influences that result in the progressive accumulation of cellular and molecular damage. Structural and Biochemical Changes with Cellular Aging
  A number of cell functions decline progressively with age.
  Oxidative phosphorylation by mitochondria is reduced, as is synthesis of nucleic acids and structural and enzymatic proteins, (...)

• phagocytosis
  23 April 2004

  WKP
  Definition: Phagocytosis is a specific form of endocytosis involving the vesicular internalization of solid particles, such as bacteria. It is therefore distinct from other forms of endocytosis such as pinocytosis, the vesicular internalization of various liquids, and recptor-dependent endocytosis.
  Phagocytosis involves three distinct but interrelated steps:
  (1) recognition and attachment of the particle to be ingested by the leukocyte;
  (2) its engulfment, with subsequent (...)

• cell death
  13 July 2003

  cell death; cellular death WKP
  Definition : Cell death is the event of a biological cell ceasing to carry out its functions. This may be the result of the natural process of old cells dying and being replaced by new ones, or may result from such factors as disease, localized injury, or the death of the organism of which the cells are part.
  Apoptosis or Type I cell-death, and autophagy or Type II cell-death are both forms of programmed cell death, while necrosis is a (...)

• cell polarity
  13 July 2003

  See also:
  epithelial polarity
  References
  Wodarz A. Molecular control of cell polarity and asymmetric cell division in Drosophila neuroblasts. Curr Opin Cell Biol. 2005 Oct;17(5):475-81. PMID: #16099639#
  Suzuki A, Hirata M, Kamimura K, Maniwa R, Yamanaka T, Mizuno K, Kishikawa M, Hirose H, Amano Y, Izumi N, Miwa Y, Ohno S. aPKC acts upstream of PAR-1b in both the establishment and maintenance of mammalian epithelial polarity. Curr Biol. 2004 Aug 24;14(16):1425-35. PMID: #15324659# (...)

• organelle transport
  16 October 2003

  organelle trafficking, organelle dynamics, organelle movement

• cellular trafficking
  16 October 2003

  Types
  vesicular trafficking
  Pathology
  anomalies of vesicular trafficking, anomalies of endosomal trafficking Griscelli disease
  anomalies of cellular trafficking hereditary spastic paraplegia
  References
  Stein M, Wandinger-Ness A, Roitbak T. Altered trafficking and epithelial cell polarity in disease. Trends Cell Biol. 2002 Aug;12(8):374-81. PMID: #12191914#
  Karcher RL, Deacon SW, Gelfand VI. Motor-cargo interactions: the key to transport specificity. Trends Cell Biol. 2002 (...)

• developmental programmed cell death
  25 June 2003
• cell-matrix signaling
  11 July 2003

  cell-extracellular matrix interaction

• cellular growth
  13 July 2003

  cell growth

• nuclear organization
  13 July 2003

  References
  Pederson T. The spatial organization of the genome in mammalian cells. Curr Opin Genet Dev. 2004 Apr;14(2):203-9. PMID: #15196468#
  Heun P, Taddei A, Gasser SM. From snapshots to moving pictures: new perspectives on nuclear organization. Trends Cell Biol. 2001 Dec;11(12):519-25. PMID: #11719059#

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