Protein

Articles

• ERBB3
  15 October 2007

  Her3

• ILK
  10 May 2005

  ILK is a serine-threonine protein kinase that associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction.
  Integrin-linked kinase (ILK) is a potent intracellular kinase involved in the regulation of multiple proliferation and survival kinases, including protein kinase B/Akt (AKT), glycogen synthase kinase-3β (GSK3β or GSK3B) and extracellular signal-regulated kinases 1 and 2 (ERK1/2 or ERK1).
  The ternary (...)

• BAP1
  15 March 2012

  BRCA1-associated protein-1 (ubiquitin carboxy-terminal hydrolase) hucep-6, KIAA0272, UCHL2
  Images
  CDKN2A FISH and BAP1 IHC in malignant mesothelioma
  https://twitter.com/PathologyTweet/status/813386502914838528
  Peritoneal malignant mesothelioma with loss of BAP-1
  https://twitter.com/sam_albadri/status/862788854708883457
  Pathology
  Germline mutations in BAP1
  in melanocytic tumors
  Germline mutations in BAP1 cause a familial tumor syndrome characterized by high penetrance for (...)

• SOX10
  9 June 2003

  Location: 22q13. SRY-BOX 10, SRY-RELATED HMG-BOX GENE 10; SRY-related HMG-box 10 (SOX10) protein PO
  Definition: SOX10 is a transcription factor known to be crucial in the specification of the neural crest and maintenance of Schwann cells and melanocytes. It is expressed in nuclei of melanocytes and breast myoepithelial cells .
  Images
  SOX10 in melanoma https://twitter.com/LisaRooperMD/status/968862378799632385
  SOX-10 NEGATIVE in basal cell carcinoma / BCC. The few positive cells (...)

• BMI1
  16 February 2006

  BMI-1

• POR
  25 April 2005

  cytochrome P40 reductase

• ESR1
  12 December 2003

  ER-alpha, estrogen receptor alpha

• GPC3
  14 July 2004

  glypican-3, glypican 3

• TFEB
  20 May 2004

  Molecular biology
  TFEB/MALAT1 fusion gene by t(6;11)(p21;q13) in
  TFEB-associated renal cell carcinoma (#15644781#, #12719541#, #12837690#)
  HMB45+ renal epithelial tumor (#11395386#)
  References
  Argani P, Lae M, Hutchinson B, Reuter VE, Collins MH, Perentesis J, Tomaszewski JE, Brooks JS, Acs G, Bridge JA, Vargas SO, Davis IJ, Fisher DE, Ladanyi M. Renal carcinomas with the t(6;11)(p21;q12): clinicopathologic features and demonstration of the specific alpha-TFEB gene fusion by (...)

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