IHC biomarker

Articles

• SALL4
  15 October 2003

  Definition: SALL4 is a member of the SALs family of proposed C(2)H(2) zinc finger transcription factors. SALL4 has important functions in embryonic stem cells.
  Pathology
  SALL4 germline mutations in the Duane radial ray syndrome (Okihiro syndrome) (MIM.607323) (#12395297#)
  Diagnostic use
  SALL4 is a novel sensitive and specific marker of ovarian pimitive germ cell tumors and is particularly useful in distinguishing ovarian Yolk sac tumor from ovarian clear cell carcinoma. (#19295406#) (...)

• INHA
  13 November 2003

  inhibin A, inhibin alpha subunit; inhibin, alpha IHCDB
  Definition: Inhibin is a polypeptide hormone secreted by granulosa cells of the ovary and Sertoli cells of the testis.
  The inhibin-alpha subunit is also expressed in other human tissues such as the prostate, brain, and adrenal cortex, as well as cells of the fetoplacental unit.
  Immunochemistry
  The alpha-inhibin immunohistochemical stain is used as a differential marker for adrenocortical tumors, placental and gestational (...)

• TNXB
  22 September 2003

  Tenascin X

• KAI1/CD82
  8 November 2005, by JA

  ST6, CD82

• CD10
  28 June 2004

  MME, calla, membrane metalloendopeptidase, neprilysin; Common Acute Lymphoblastic Leukemia Antigen (CALLA), neutral endopeptidase 24.11, neprilysin, enkephalinase WKP PathologyOutlines HGNC PO
  See also: MME
  Definition: Cell membrane metallopeptidase expressed by early B, pro-B and pre-B lymphocytes, and by lymph node germinal centers.
  CD10 is widely distributed in normal tissue, including brush border of small bowel mucosa.
  CD10 is also expressed in neoplasms (epithelial cells and (...)

• PDPN
  22 December 2005

  podoplanin

• VIM
  19 March 2005

  vimentin

0 | 10 | 20 | 30