Cellular lesions

Articles

• sea-blue histiocytes
  18 January 2006

  sea blue histiocytes, histiocytes "bleu de mer", acquired lipidosis of marrow macrophages

• cytoskeletal anomalies
  4 February 2006

  Abnormalities of the cytoskeleton underlie a variety of pathologic states.
  The normal cytoskeleton
  The cytoskeleton consists of microtubules (20 to 25 nm in diameter), thin actin filaments (6 to 8 nm), thick myosin filaments (15 nm), and various classes of intermediate filaments (10 nm). Several other nonpolymerized and nonfilamentous forms of contractile proteins also exist.
  Cytoskeletal abnormalities may be reflected by: (1) defects in cell function, such as cell locomotion and (...)

• pseudo-Gaucher cell
  29 December 2006

  pseudo-Gaucher histiocytes, pseudo-Gaucher macrophages

• foamy macrophages in the spleen
  20 July 2007

  Etiology
  infections mycobacterioses Mycobacterium avium intracellulare infection (MAI infection) (Case 12002)
  metabolic diseases storage diseases
  Case records
  Case 12002 : Systemic granulomatosis in Mycobacterium avium intracellulare
  See also
  medullary macrophages
  splenic macrophages

• cryptic apoptotic bodies
  18 October 2004

  crypt apoptotic bodies; crypt apoptotic body
  Images
  colorectal GVHD
  https://twitter.com/Pathologists/status/742099178583515137
  https://twitter.com/stephen_lagana/status/736578297153327104
  Histopathology assessment is crucial for the diagnosis of graft versus host disease (GVHD), as the presence of crypt apoptosis is the cardinal criterion required.
  However, crypt apoptosis is not limited to GVHD; it also occurs in other conditions such as infection, drug reaction, or inflammatory (...)

• lipofuscin deposits
  8 January 2006

  Definition: Lipofuscin pigment granules represent undigested material derived from intracellular lipid peroxidation.
  Images
  Lipofuscin is the "wear-and-tear" pigment of the heart. Morphologically found at the myocytes’ nuclear "poles" https://twitter.com/MelanieBoisMD/status/807701991782842369
  Wikimedia: intestinal melanosis
  Localization
  cardiomyocytic lipofuscin deposits
  hepatocytic lipofuscin deposits
  Kupffer cells lipofuscin deposits
  lipofuscin (...)

• biliary epithelial dysplasia
  29 August 2008

  Etiology
  Clonorchis sinensis
  choledochal cyst
  gallbladder dysplasia
  See also
  biliary epithelial lesions

• epithelial dysplasias
  20 June 2007

  epithelial dysplasia

• Rosenthal fibers
  16 April 2005

  Rosenthal fiber inclusions
  Definition: Subtype of intermediate filament inclusions formed by aggregation of glial fibrillary acidic protein (GFAP ).
  Images
  Incidental, but large pineal cyst. Frequent Rosenthal fibres in cyst wall are typical. https://twitter.com/neuropathobern/status/859447047677779972
  Pathology
  Alexander disease
  pilocytic astrocytoma Image : https://twitter.com/rxmsimages/status/718719835723603968
  pineal (...)

• nuclear inclusions
  4 April 2005

  Definition: Abnormal substances in the nuclei that can be observed by light microscopy are often broadly referred to as nuclear inclusions.
  Images
  Nuclear pseudoinclusions in adrenal cortical adenoma
  https://twitter.com/a_sleeping_dog/status/766154834185641984
  Types
  nuclear pseudoinclusions
  nuclear viral inclusions
  Although their recognition in the appropriate clinicopathological settings can aid in the diagnosis of some disease entities and tumor types, they can also be a (...)

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