Cellular lesions

Articles

• cytoskeletal anomalies
  4 February 2006

  Abnormalities of the cytoskeleton underlie a variety of pathologic states.
  The normal cytoskeleton
  The cytoskeleton consists of microtubules (20 to 25 nm in diameter), thin actin filaments (6 to 8 nm), thick myosin filaments (15 nm), and various classes of intermediate filaments (10 nm). Several other nonpolymerized and nonfilamentous forms of contractile proteins also exist.
  Cytoskeletal abnormalities may be reflected by: (1) defects in cell function, such as cell locomotion and (...)

• epithelial dysplasia
  20 June 2007

  epithelial dysplasia

• pseudo-Gaucher cell
  29 December 2006

  pseudo-Gaucher histiocytes, pseudo-Gaucher macrophages

• lipofuscin deposits
  8 January 2006

  Definition: Lipofuscin pigment granules represent undigested material derived from intracellular lipid peroxidation.
  Images
  Lipofuscin is the "wear-and-tear" pigment of the heart. Morphologically found at the myocytes’ nuclear "poles" https://twitter.com/MelanieBoisMD/status/807701991782842369
  Wikimedia: intestinal melanosis
  Localization
  cardiomyocytic lipofuscin deposits
  hepatocytic lipofuscin deposits
  Kupffer cells lipofuscin deposits
  lipofuscin (...)

• cholesterol crystals
  3 December 2005

  cholesterol clefts; Cholesterol crystal clefts
  Images
  aortic atherosclerotic plaque Image: https://twitter.com/BeynonMD/status/718292728862400512
  cholesterol embolism / cholesterol embolus with cholesterol clefts https://twitter.com/BethBraunhut/status/877208580209999876
  Cholesterol crystal clefts and foreing-body giant cells found in radicular cyst https://twitter.com/reportesVilla/status/879410114914136064
  See also (...)

• intramacrophagic crystals
  2 December 2005
• hepatocytic PAS+ non-glycogenic globules
  12 March 2007

  Periodic acid Schiff-positive non-glycogenic globules in hepatocytes

• cytoplasmic globules
  12 March 2007

  Etiology
  in diseases alpha-1-antitrypsine deficiency rete testis hyperplasia with hyaline globule formation (#1702268#)
  in tumors endodermal sinus tumor (yolk sac tumor) infantile digital fibroma vascular tumors malignant rhabdoid tumor (MRT) (#3030922#) eosinophilic intracytoplasmic globules in pulmonary adenocarcinoma(#2476374#)
  Localization
  in hepatocytes alpha-1-antitrypsine deficiency
  See also
  hyaline globules
  matrix globules
  hepatocytic PAS+ non-glycogenic (...)

• esophageal epithelial apoptotic bodies
  25 February 2005

  oesophageal epithelial apoptotic bodies

• sea-blue histiocytes
  18 January 2006

  sea blue histiocytes, histiocytes "bleu de mer", acquired lipidosis of marrow macrophages

0 | 10 | 20 | 30