Cellular lesions

Articles

• cytoskeletal anomalies
  4 February 2006

  Abnormalities of the cytoskeleton underlie a variety of pathologic states.
  The normal cytoskeleton
  The cytoskeleton consists of microtubules (20 to 25 nm in diameter), thin actin filaments (6 to 8 nm), thick myosin filaments (15 nm), and various classes of intermediate filaments (10 nm). Several other nonpolymerized and nonfilamentous forms of contractile proteins also exist.
  Cytoskeletal abnormalities may be reflected by: (1) defects in cell function, such as cell locomotion and (...)

• sea-blue histiocytes
  18 January 2006

  sea blue histiocytes, histiocytes "bleu de mer", acquired lipidosis of marrow macrophages

• nuclear inclusions
  4 April 2005

  Definition: Abnormal substances in the nuclei that can be observed by light microscopy are often broadly referred to as nuclear inclusions.
  Images
  Nuclear pseudoinclusions in adrenal cortical adenoma
  https://twitter.com/a_sleeping_dog/status/766154834185641984
  Types
  nuclear pseudoinclusions
  nuclear viral inclusions
  Although their recognition in the appropriate clinicopathological settings can aid in the diagnosis of some disease entities and tumor types, they can also be a (...)

• epithelial dysplasia
  20 June 2007

  epithelial dysplasia

• crystals
  3 December 2005

  Localization
  intracellular crystals
  extracellular crystals crystals in synovial fluid
  Types
  cholesterol crystals
  urate crystals
  oxalate crystals
  tyrosine crystals
  Associations
  crystals in prostatic adencoarcinoma https://twitter.com/ridenoro/status/734953635021393921
  calcium oxalate crystalsin Aspergillus niger infection in ear https://twitter.com/hematogones/status/822175383047077889
  See also
  deposits tissular deposits crystal (...)

• lipofuscin deposits
  8 January 2006

  Definition: Lipofuscin pigment granules represent undigested material derived from intracellular lipid peroxidation.
  Images
  Lipofuscin is the "wear-and-tear" pigment of the heart. Morphologically found at the myocytes’ nuclear "poles" https://twitter.com/MelanieBoisMD/status/807701991782842369
  Wikimedia: intestinal melanosis
  Localization
  cardiomyocytic lipofuscin deposits
  hepatocytic lipofuscin deposits
  Kupffer cells lipofuscin deposits
  lipofuscin (...)

• syncitial cells
  18 March 2007

  Digital slides
  JRC:14069 : Lung metastasis of a choriocarcinoma from mediastinum.
  Examples
  normal tissue syncytiotrophoblast
  lesional conditions giant cell transformations of hepatocytes
  syncitial cell tumors choriocarcinoma
  See also
  syncitium

• polyglucosan bodies
  3 January 2006

  polyglucosan body, polyglucosan inclusions, corpus amylaceum

• esophageal epithelial apoptotic bodies
  25 February 2005

  oesophageal epithelial apoptotic bodies

• pseudo-Gaucher cell
  29 December 2006

  pseudo-Gaucher histiocytes, pseudo-Gaucher macrophages

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