Cellular lesions

Articles

• cytoskeletal anomalies
  4 February 2006

  Abnormalities of the cytoskeleton underlie a variety of pathologic states.
  The normal cytoskeleton
  The cytoskeleton consists of microtubules (20 to 25 nm in diameter), thin actin filaments (6 to 8 nm), thick myosin filaments (15 nm), and various classes of intermediate filaments (10 nm). Several other nonpolymerized and nonfilamentous forms of contractile proteins also exist.
  Cytoskeletal abnormalities may be reflected by: (1) defects in cell function, such as cell locomotion and (...)

• vacuolated Kuppfer cells
  29 July 2008

  Etiology (Examples)
  galactosialidosis (MIM.256540)

• hepatocytic PAS+ non-glycogenic globules
  12 March 2007

  Periodic acid Schiff-positive non-glycogenic globules in hepatocytes

• lipofuscin deposits
  8 January 2006

  Definition: Lipofuscin pigment granules represent undigested material derived from intracellular lipid peroxidation.
  Images
  Lipofuscin is the "wear-and-tear" pigment of the heart. Morphologically found at the myocytes’ nuclear "poles" https://twitter.com/MelanieBoisMD/status/807701991782842369
  Wikimedia: intestinal melanosis
  Localization
  cardiomyocytic lipofuscin deposits
  hepatocytic lipofuscin deposits
  Kupffer cells lipofuscin deposits
  lipofuscin (...)

• lipofuscin deposits in digestive smooth muscle cells
  8 January 2006

  See also
  lipofuscin deposits
  digestive smooth muscle cells

• sea-blue histiocytes
  18 January 2006

  sea blue histiocytes, histiocytes "bleu de mer", acquired lipidosis of marrow macrophages

• Rosenthal fibers
  16 April 2005

  Rosenthal fiber inclusions
  Definition: Subtype of intermediate filament inclusions formed by aggregation of glial fibrillary acidic protein (GFAP ).
  Images
  Incidental, but large pineal cyst. Frequent Rosenthal fibres in cyst wall are typical. https://twitter.com/neuropathobern/status/859447047677779972
  Pathology
  Alexander disease
  pilocytic astrocytoma Image : https://twitter.com/rxmsimages/status/718719835723603968
  pineal (...)

• cryptic apoptotic bodies
  18 October 2004

  crypt apoptotic bodies; crypt apoptotic body
  Images
  colorectal GVHD
  https://twitter.com/Pathologists/status/742099178583515137
  https://twitter.com/stephen_lagana/status/736578297153327104
  Histopathology assessment is crucial for the diagnosis of graft versus host disease (GVHD), as the presence of crypt apoptosis is the cardinal criterion required.
  However, crypt apoptosis is not limited to GVHD; it also occurs in other conditions such as infection, drug reaction, or inflammatory (...)

• biliary epithelial dysplasia
  29 August 2008

  Etiology
  Clonorchis sinensis
  choledochal cyst
  gallbladder dysplasia
  See also
  biliary epithelial lesions

• cholesterol crystals
  3 December 2005

  cholesterol clefts; Cholesterol crystal clefts
  Images
  aortic atherosclerotic plaque Image: https://twitter.com/BeynonMD/status/718292728862400512
  cholesterol embolism / cholesterol embolus with cholesterol clefts https://twitter.com/BethBraunhut/status/877208580209999876
  Cholesterol crystal clefts and foreing-body giant cells found in radicular cyst https://twitter.com/reportesVilla/status/879410114914136064
  See also (...)

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