Cancer gene

Articles

• IDH1
  2 September 2010

  Immunochemistry
  Differentiation of gliomas and reactive gliosis may be challenging both at primary tumor occurrence and at posttherapy biopsy.
  The most frequent IDH1 mutation found in the majority of WHO grade II and III gliomas can be visualized with an antibody specifically detecting mutant IDH1 protein.
  mIDH1R132H is a tumor-specific marker that is superior to other established markers to differentiate reactive from neoplastic cells in grade II and III gliomas and allows identifying (...)

• ADAM9
  14 September 2004

  Pathology
  ADAM9 to be distinctly overexpressed in pancreatic ductal adenocarcinoma ADAM9 expression in pancreatic cancer is associated with tumour type and is a prognostic factor in ductal adenocarcinoma (#14997207#)

• FLCN
  27 November 2004

  folliculin, FLCL

• RAF1
  22 November 2004

  CRAF, c-raf, Raf-1, c-Raf, CRAF, v-raf-1 murine leukemia viral oncogene homolog 1

• FAM123B
  18 June 2007

  WTX, family with sequence similarity 123, member 123

• TFE3
  1 December 2003

  TFE3, a member of the helix-loop-helix family of transcription factors, binds to the mu-E3 motif of the immunoglobulin heavy-chain enhancer and is expressed in many cell types.
  Pathology
  TFE3-ASPL gene fusion by t(X;17)(p11;q25) in
  juvenile renal cell carcinoma
  alveolar soft part sarcoma (#12769020#)
  Fusion SFPQ/TFE3 gene in papillary renal cell carcinoma (#9393982#)
  A distinctive subset of PEComas harbors TFE3 gene fusions (#20871214#)
  Perivascular Epithelioid Cell Tumor With (...)

• MGEA5
  13 January 2017

  |WKP|
  Definition: Bifunctional protein NCOAT is a protein that in humans is encoded by the MGEA5 gene.
  Pathology
  Consistent t(1;10) with rearrangements of TGFBR3 and MGEA5 in : myxoinflammatory fibroblastic sarcoma (#21717526#) hemosiderotic fibrolipomatous tumor (#21717526#) PHAT pleomorphic hyalinizing angiectatic tumor
  Open References
  Consistent t(1;10) with rearrangements of TGFBR3 and MGEA5 in both myxoinflammatory fibroblastic sarcoma and hemosiderotic fibrolipomatous (...)

• GPC5
  21 September 2004

  glypican-5, GLYPICAN 5, GPC5

• STAT3
  29 November 2004

  signal transducer and activator of transcription 3 (acute-phase response factor)

• NAB2
  9 September 2015

  WKP
  Pathology
  NAB2-STAT6 gene fusion NAB2-STAT6 gene fusion in solitary fibrous tumor (SFT) (#26337721#) Identification of recurrent NAB2-STAT6 gene fusions in solitary fibrous tumor by integrative sequencing. (#23313952#, #23313954#)
  Open references
  A GRIA2 and PAX8-positive renal solitary fibrous tumor with NAB2-STAT6 gene fusion. Ichiyanagi O, Ito H, Takai S, Naito S, Kato T, Nagaoka A, Yamakawa M. Diagn Pathol. 2015 Sep 4;10(1):155. doi:10.1186/s13000-015-0386-x . PMID: (...)

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