Cancer gene

Articles

• MAML2
  8 March 2004

  Mastermind-like Notch coactivator MAML2
  Pathology
  MAML2-MECT1 (MAMl2-CRTC1) gene fusion by t(11;19)(q21;p13) in
  mucoepidermoid carcinoma (#14720503#)
  benign Warthin tumor (#14720503#)
  cutaneous clear cell hidradenoma (#15729701#, #17334997#)
  MAML2-WAMTP1 gene fusion
  MAML2-MLL gene fusion in
  secondary acute myelogenous leukemia (#17551948#)
  myelodysplastic syndrome with inv(11)(q21q23) (#17551948#)
  The MECT1-MAML2 translocation is identified in a large proportion of (...)

• MALAT1
  26 June 2007

  metastasis-associated lung adenocarcinoma transcript 1

• JAK2
  8 November 2005

  Janus activated kinase 2

• ATF1
  14 October 2003

  ATF-1

• ERBB2
  11 February 2006

  ERBB2 ; CD340; HER-2; HER-2/neu; HER2; MLN 19; NEU; NGL; TKR1; c-erbb2
  The oncogene originally called HER/NEU was derived from rat neuro/glioblastoma cell lines. It encodes a tumor antigen, p185, which is serologically related to EGFR, the epidermal growth factor receptor (MIM.131550).
  ERBB2 encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases (ERBBs).
  ERBB2 has no ligand binding domain of its own and therefore cannot bind growth factors. (...)

• FAM123B
  18 June 2007

  WTX, family with sequence similarity 123, member 123

• CHEK1
  12 March 2006

  CHK1

• CDH1
  20 December 2007

  E-cadherin, cadherin-1, uvomorulin, epithelial cadherin WP HGNC PO
  Definition: Tumor suppressor gene CDH1 is at 16q22.1 Calcium-dependent transmembrane epithelial protein that promotes intercellular adhesion.
  Cadherin-1 (cadherin-E) is a specific calcium ion-dependent cell adhesion molecule. E-cadherin is simultaneously a major cell-adhesion molecule, a tumour suppressor protein, a determinant of cell polarity and a partner to the potent catenin signalling molecules.
  Its loss is (...)

• POU5F1
  13 July 2004

  Oct-4, OCT4, OCT3, OTF4, OTF3

• NUP214
  19 June 2007

  CAN/Nup214

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