Cancer gene

Articles

• NUP214
  19 June 2007

  CAN/Nup214

• PDGFRA
  12 December 2003

  platelet-derived growth factor receptor (PDGFR) alpha, PDGFR-alpha

• FAM123B
  18 June 2007

  WTX, family with sequence similarity 123, member 123

• CABLES1
  5 June 2007

  CDK5 and ABL enzyme substrate 1

• MAP3K5
  28 June 2004

  ASK1

• CIC
  30 January 2008

  Protein capicua homolog CIC
  Definition: CIC, a human homolog of Drosophila capicua which encodes a high mobility group box transcription factor, is fused to a double homeodomain gene DUX4 as a result of a recurrent chromosomal translocation t(4;19)(q35;q13).
  Molecular biology
  CIC-DUX4 fusion gene between DUX4 at 4q35 (MIM.606009) and CIC at 19q35 by t(4;19)(q35;q13) (#16717057#) in Ewing-like sarcoma
  CIC-rearranged undifferentiated round-cell sarcoma with exclusive spindled (...)

• TFPT
  26 June 2007

  TCF3 fusion partner

• PTK2B
  28 February 2008

  protein-tyrosine kinase 2 beta

• EMS1
  31 January 2007

  cortactin,

• MAP4
  11 September 2007

  Pathology
  MALT1/MAP4 fusion gene in diffuse large B-cell lymphoma (#16804917#)
  References
  Murga Penas EM, Kawadler H, Siebert R, Frank M, Ye H, Hinz K, Becher C, Hummel M, Barth TF, Bokemeyer C, Stein H, Trumper L, Moller P, Marynen P, Du MQ, Yang X, Hansmann ML, Dierlamm J. A novel fusion of the MALT1 gene and the microtubule-associated protein 4 (MAP4) gene occurs in diffuse large B-cell lymphoma. Genes Chromosomes Cancer. 2006 Sep;45(9):863-73. PMID: (...)

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