Involved in translocations

Articles

• AF9
  3 June 2004

  Pathology
  AF9/MLL fusion gene from translocation t(9;11)(p22;q23) in acute myeloid leukemia

• TLX1
  8 November 2005

  T-cell leukemia homeobox 1, HOX11, TCL3

• ABL
  7 June 2004

  Abelson

• FIP1L1
  9 February 2006

  Pathology
  PDGFRA/FIP1L1 gene fusion in
  chronic eosinophilic leukemia (idiopathic hypereosinophilic syndrome) (MIM.607685)
  eosinophilia-associated acute myeloid leukemia (#17377585#)
  lymphoblastic T-cell lymphoma (#17377585#)
  References
  Vigna E, Lucia E, Gentile M, Mazzone C, Bisconte MG, Gentile C, Armentano A, Ottaviani E, Rondoni M, Martinelli G, Morabito F. PDGFRalpha/FIP1L1-positive chronic eosinophilic leukemia presenting with retro-orbital localization: efficacy of imatinib (...)

• MYC
  29 October 2003

  c-MYC

• FHIT
  5 March 2006

  Pathology
  The constitutional translocation t(3;8)(p14.2;q24.1) fuses FHIT at 3p14 with the patched-related gene TRC8 at 8q24.1 (#9689122#) with formation of the TRC8/FHIT fusion gene). It predisposes to
  hereditary renal clear cell carcinoma (#17539022#)
  hereditary renal clear cell carcinoma and non-medullary thyroid cancer (#470981#, #12522559#, #17539022#)
  TRC8 hereditary kidney cancer gene suppresses growth and functions with VHL in a common pathway (#12032852#)
  References (...)

• PBX1
  8 June 2004

  Pathology
  PBX1-TCF3 fusion gene by t(1;19)(q23;13.3) in : B-lineage acute lymphoblastic leukemia
  EWSR1-PBX1 fusion gene in : myoepithelial tumors (#26645726#)
  Paywall References
  Thoracic Myoepithelial Tumors: A Pathologic and Molecular Study of 8 Cases With Review of the Literature. Leduc C, Zhang L, Öz B, Luo J, Fukuoka J, Antonescu CR, Travis WD. Am J Surg Pathol. 2016 Feb;40(2):212-23. doi:10.1097/PAS.0000000000000560. PMID: (...)

• EVI1
  28 June 2004

  MDS

• MLLT2
  2 March 2005

  AF4

• BCR
  7 June 2004

  Pathology
  BCR/ABL fusion gene in B-lineage acute lymphoblastic leukemia by t(9;22)(q34;q11)
  BCR expression is decreased in meningiomas showing loss of heterozygosity of 22q (22q11 LOH) (#18474292#)
  References
  Wozniak K, Piaskowski S, Gresner SM, Golanska E, Bieniek E, Bigoszewska K, Sikorska B, Szybka M, Kulczycka-Wojdala D, Zakrzewska M, Zawlik I, Papierz W, Stawski R, Jaskolski DJ, Och W, Sieruta M, Liberski PP, Rieske P. BCR expression is decreased in meningiomas showing loss of (...)

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