Definition: Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma of childhood. Rhabdomyosarcoma is a soft tissue tumor of striated muscle origin. It is observed mainly in children and adolescents.
Images
Alveolar rhabdomyosarcoma. PCR: pos PAX3-FOXO1 (worse prognosis c/w PAX7). Scattered MNGC rhabdomyoblasts.
https://twitter.com/histiocytosisX/status/699599913013923840
ARMS : focal desmin w/ diffuse myogenin in A-RMS (PCR + PAX3-FOXO1) (...)
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Macroscopy
Articles
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rhabdomyosarcomas
25 November 2003 -
hepatoblastoma
16 March 2004hepatoblastomas
Definition: Hepatoblastoma is a malignant embryonal liver tumor that occurs almost exclusively in infants and very young children.
Image
Macroscopy : https://twitter.com/DraEosina/status/762631086207893506
Cytology: https://twitter.com/AdamGomezMD/status/720632495671087104
https://twitter.com/MArnold_PedPath/status/736000944303808512
Hepatoblastoma is composed of epithelial and mesenchymal elements in varying proportions and at various stages of differentiation. The (...) -
congenital pulmonary airway malformation
18 December 2003CCAM, CAM, congenital cystic adenomatoid malformations, CPAMs; congenital pulmonary airway malformations; Lung Cystic adenomatoid transformation. Ent. 1897, Nom. 2002
Digital cases (Digital slides)
HPC:104 : CPAM type 2
HPC:370 : Cystic congenital adenomatoid malformation in extrapulmonary sequestration.
JRC:6291 : Lung cystic adenomatoid transformation.
JRC:6292 : Lung cystic adenomatoid transformation.
JRC:6298 : Lung cystic adenomatoid transformation.
Definition: CPAM is a (...) -
endometrial polyp
17 November 2004Clinical synopsis
asymptomatic or associated with bleeding
associated with tamoxifen therapy for breast cancer
Macroscopy synopsis
sessile or pedunculated mass
cystically dilated glands
multicystic cut surface
Microscopy synopsis
endometrial glands unresponsive to progesterone stimulation
may have severe atypia
fibrous stroma with spindled
fibroblast-like cells
abundant extracellular connective tissue
polypoid shape
attenuated surface endometrium on 3 sides (...) -
necrosis
9 November 2004tissular death
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colorectal adenoma
12 May 2004colorectal adenomas
Definition: Adenomas, the benign glandular neoplasms that precede colon cancer development, originate from the intestinal epithelium. They occur singly or multiply. When multiple, the patients may have a genetic predisposition syndrome for colorectal cancer.
See also : colorectal adenoma with adenocarcinoma
Endoscopy
Small (< 5 mm) colorectal polyps commonly affect individuals older than 50 years of age and adenomas account for 60% to 66% ofthese small lesions. (...) -
Wilson disease
30 May 2003Wilson’s disease
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Wilms tumor
14 November 2003nephroblastoma
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testicular teratoma
18 July 2004Teratoma of the testis
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ovotesticular DSD
22 December 2005true hermaphrodism, ovotesticular DSD, ovotesticular disorder of sexual differentiation, true hermaphroditism
Definition: Presence of both ovarian and testicular tissue in the same gonad (ovotesis) or in a contralateral gonad (ovary on one side, testis on another one). (Formerly: true hermaphroditism)
True hermaphroditism is defined as the presence of both testicular and ovarian tissue in a patient. Affected individuals may have either a female or a male phenotype with variable degrees of (...)
