Humpath.com - Human pathology

Home > E. Pathology by systems > Digestive system > Liver and pancreatobiliary system > Liver > ciliated hepatic foregut cyst

ciliated hepatic foregut cyst

Thursday 8 June 2006

Ciliated hepatic foregut cyst (CHFC) is a rare, benign, solitary cyst consisting of ciliated pseudostratified columnar epithelium, subepithelial connective tissue, a smooth muscle layer, and an outer fibrous capsule.

The epithelium lining ciliated hepatic foregut cysts has histological, histochemical, and immunohistochemical features similar to those observed in the bronchiolar epithelium. This lesion is a developmental ventral foregut abnormality that could arise from a bronchiolar bud of the tracheobronchial diverticulum. (10685641)

Synopsis

- lining of the columnar epithelium composed of ciliated cells and mucin secreting goblet cells (10685641)
- wall composed of bands of smooth-muscle fibers surrounded by an outer fibrous capsule (10685641)

Immunochemistry

- endocrine cells within the cyst epithelium, positive for chromogranin, synaptophysin, bombesin, and calcitonin, and negative for serotonin, somatostatin, glucagon, insulin, gastrin, and pancreatic polypeptide (10685641)

References

- Young AS, Nicol KK, Teich S, Ii WE. Catheter-based drainage and agitation for definitive cytological diagnosis of a ciliated hepatic foregut cyst in a child. Pediatr Dev Pathol. 2007 Mar-Apr;10(2):153-6. PMID: 17378692

- Chatelain D, Chailley-Heu B, Terris B, Molas G, Le Cae A, Vilgrain V, Belghiti J, Degott C, Flejou JF. The ciliated hepatic foregut cyst, an unusual bronchiolar foregut malformation: a histological, histochemical, and immunohistochemical study of 7 cases. Hum Pathol. 2000 Feb;31(2):241-6. PMID: 10685641

- Vick DJ, Goodman ZD, Deavers MT, Cain J, Ishak KG. Ciliated hepatic foregut cyst: a study of six cases and review of the literature. Am J Surg Pathol. 1999 Jun;23(6):671-7. PMID: 10366149

- Sato Y, Kitagawa S, Zen Y, Minato H, Nakanuma Y. Ciliated hepatic cyst without smooth muscle layer: A variant of ciliated hepatic foregut cyst? Pathol Int. 2006 Jun;56(6):340-4. PMID: 16704499

- Vick DJ, Goodman ZD, Deavers MT, Cain J, Ishak KG. Ciliated hepatic foregut cyst: a study of six cases and review of the literature. Am J Surg Pathol. 1999 Jun;23(6):671-7. Review. PMID: 10366149

- Terada T, Nakanuma Y, Kono N, Ueda K, Kadoya M, Matsui O. Ciliated hepatic foregut cyst. A mucus histochemical, immunohistochemical, and ultrastructural study in three cases in comparison with normal bronchi and intrahepatic bile ducts. Am J Surg Pathol. 1990 Apr;14(4):356-63. PMID: 2321699

- Wheeler DA, Edmondson HA. Ciliated hepatic foregut cyst. Am J Surg Pathol. 1984 Jun;8(6):467-70. PMID: 6731667