Saturday 3 June 2006
The trans-Golgi network (TGN) is a major sorting centre for cell lipids and proteins at the crossroads of the endocytic and exocytic pathways; it has a complex dynamic structure composed of a network of tubular membranes that generate pleiomorphic carriers targeted to different destinations.
Traub LM, Kornfeld S. The trans-Golgi network: a late secretory sorting station. Curr Opin Cell Biol 1997;9:527-53
Shields D, Arvan P. Disease models provide insights into post-Golgi protein trafficking, localization and processing. Curr Opin Cell Biol 1999;11:489-494