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Home > G. Tumoral pathology > Molecular pathology of tumors > Genetic anomalies > Cancer cytogenetics > Tumoral translocations > t(2;5)(p23;q35)


Tuesday 21 March 2006

ALK at 2p23 and NPM1 at 5q35


- anaplasic large cell lymphoma (ALCL)
- rare plasmablastic lymphoma (diffuse large B-cell lymphoma of plasmablastic type) (14576483)

See also

- ALK rearrangements in 2p23

  • t(X;2)(q11;p23)
  • t(1;2)(q25;p23)
  • inv(2)(p23q35)
  • t(2;3)(p23;q21)
  • t(2;17)(p23;q23)
  • t(2;19)(p23; p13.1)
  • t(2;22)(p23;q11.2)


- Adam P, Katzenberger T, Seeberger H, Gattenlohner S, Wolf J, Steinlein C, Schmid M, Muller-Hermelink HK, Ott G. A case of a diffuse large B-cell lymphoma of plasmablastic type associated with the t(2;5)(p23;q35) chromosome translocation. Am J Surg Pathol. 2003 Nov;27(11):1473-6. PMID: 14576483

- Cataldo KA, Jalal SM, Law ME, Ansell SM, Inwards DJ, Fine M, Arber DA, Pulford KA, Strickler JG.Detection of t(2;5) in anaplastic large cell lymphoma: comparison of immunohistochemical studies, FISH, and RT-PCR in paraffin-embedded tissue.Am J Surg Pathol. 1999 Nov;23(11):1386-92. PMID: 10555007

- t(2;5)(p23;q35) at AGCOH