Home > E. Pathology by systems > Genital system > Leydig cell tumor

Leydig cell tumor

Monday 13 February 2006

Digital cases

- HPC:119 : Leydig cell tumor.
- JRC:18782 : Testis intestitial cell tumor

Synopsis

- Leydig cell proliferation

  • round cell proliferation
  • fusiform cell proliferation

- Leydig cells

  • abundant eosinophilic cytoplasm
  • characteristic nuclear-rich zones separated by nuclear-free zones
  • crystals of Reinke (Reinke crystals)

Localization

- ovarian Leydig cell tumor
- testicular Leydig cell tumor

  • paratesticular Leydig cell tumor

Variants

- microcystic Leydig cell tumor (#10328086#)

Differential diagnosis

- yolk sac tumor (#10328086#)

See also

- Sertoli-stromal cell tumors

  • Sertoli cell tumor (SCT)
  • large cell calcifying Sertoli cell tumor (LCCSCT)
  • Sertoli-Leydig cell tumor
  • Leydig cell tumor (Leydig cell adenoma)
  • Leydig cell hyperplasia

References

- Billings SD, Roth LM, Ulbright TM. Microcystic Leydig cell tumors mimicking yolk sac tumor: a report of four cases. Am J Surg Pathol. 1999 May;23(5):546-51. PMID: #10328086#

Portfolio

  • Multiple Leydig cell and Sertoli cell adenomas in androgen insentivity (...)
  • Multiple Leydig cell and Sertoli cell adenomas in androgen insentivity (...)
  • Ovarian Leydig cell tumor
  • Ovarian Leydig cell tumor
  • Ovarian Leydig cell tumor
  • Ovarian Leydig cell tumor
  • Ovarian Leydig cell tumor
  • Ovarian Leydig cell tumor
  • Ovarian Leydig cell tumor
  • Ovarian Leydig cell tumor
  • Ovarian Leydig cell tumor
  • Ovarian Leydig cell tumor
  • Ovarian Leydig cell tumor
  • Ovarian Leydig cell tumor
  • Ovarian Leydig cell tumor
  • Ovarian Leydig cell tumor
  • Paratesticular Leydig cell tumor
  • Paratesticular Leydig cell tumor
  • Paratesticular Leydig cell tumor
  • Paratesticular Leydig cell tumor
  • Paratesticular Leydig cell tumor
  • Paratesticular Leydig cell tumor
  • Paratesticular Leydig cell tumor
  • Paratesticular Leydig cell tumor
  • Paratesticular Leydig cell tumor
  • Paratesticular Leydig cell tumor
  • Paratesticular Leydig cell tumor
  • Paratesticular Leydig cell tumor - Cytokeratin -
  • Paratesticular Leydig cell tumor - Inhibin +
  • Paratesticular Leydig cell tumor - Inhibin +
  • Paratesticular Leydig cell tumor - Ki67 -
  • Paratesticular Leydig cell tumor - Vimentin +