Humpath.com - Human pathology

Home > E. Pathology by systems > Reproductive system > Sertoli-Leydig cell tumor

Sertoli-Leydig cell tumor

Monday 13 February 2006

Sertoli-Leydig cell tumours of the ovary and testis; Sertoli-leydig tumor

Images

- Sertoli-leydig cell tumor

Digital cases

- JRC:1455 : Ovary Sertoli-Leydig cell tumor (poorly differentiated, with heterologous mucinous component).
- JRC:9205 : Ovary Sertoli-Leydig cell tumor.
- JRC:9209 : Ovary Sertoli-Leydig cell tumor.
- JRC:9215 : Ovary Sertoli-Leydig cell tumor.
- JRC:9221 : Ovary Sertoli-Leydig cell tumor.
- JRC:1648 : Cystic stromal tumor of ovary Sertoli-Leydig versus granulosa cell tumor.
- JRC:2604 : Ovary Sertoli-Leydig cell tumor.
- JRC:340 : Ovary Sertoli-Leydig cell tumor. (? with focal retiform features)

Links

- Sertoli-Leydig Cell Tumor at WebPathology

Synopsis

- multicystic with solid areas
- cyst can be filled with chocolate-brown material

Variants

- well-differentiated sertoli-leydig cell tumor.

Localization

- ovarian Sertoli-Leydig cell tumor
- testicular Sertoli-Leydig cell tumor

CGH

- The DNA copy number changes affected chromosome 1, 8, 9p, 10, 11, 12, 16, 19, 22 and X. (17235570)
- isolated trisomy 8 (11381376)

See also

- Sertoli-stromal cell tumors

References

- Sertoli-Leydig cell tumours of the ovary and testis: a CGH and FISH study. Verdorfer I, Horst D, Höllrigl A, Rogatsch H, Mikuz G. Virchows Arch. 2007 Mar;450(3):267-71. PMID: 17235570

- Trisomy 8 as sole karyotypic aberration in an ovarian metastasizing Sertoli-Leydig cell tumor. Manegold E, Tietze L, Günther K, Fleischer A, Amo-Takyi BK, Schröder W, Handt S. Hum Pathol. 2001 May;32(5):559-62. PMID: 11381376