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MIM.179410 11q23

Monday 6 February 2006

Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane.

RDX has a significant homology in sequence to VIL2 (ezrin) (MIM.123900), EBP41 (protein 4.1) (MIM.130500), TLN1 (talin)(MIM.186745), MSN and NF2 (merlin) (MIM.607379).

These proteins constitute a family with structural and probably functional relationships; all of them are localized to the submembranous cytoskeleton (See ERM proteins).