Wednesday 18 January 2006
Cancer is a product of genetic mutations and errors in epigenetic regulation.
However, the potential of these malignant changes to cause disease is significantly regulated by the host immune system.
- cancer prevention
- cancer progression
- immunologic control of cancer
- immunologic shaping of cancer
regulation of the immune system by tumors
Finn OJ. Cancer immunology. N Engl J Med. 2008 Jun 19;358(25):2704-15. PMID: 18565863
de Visser KE, Eichten A, Coussens LM. Paradoxical roles of the immune system during cancer development. Nat Rev Cancer. 2006 Jan;6(1):24-37. PMID: 16397525