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invasive candidiasis - Humpath.com - Human pathology

Home > D. General pathology > Infectious diseases > invasive candidiasis

invasive candidiasis

Wednesday 7 December 2005

Invasive candidiasis is caused by blood-borne dissemination of Candida to various tissues or organs.

Synopsis

- renal abscesses
- myocardial abscesses
- endocarditis
- meningitis
- cerebral microabscesses
- endophthalmitis
- hepatic abscesses
- Candida pneumonia
- Candida endocarditis

  • most common fungal endocarditis
  • usually occurring in the setting of prosthetic heart valves or in intravenous drug abusers.

In any of these locations, the fungus may evoke little or no inflammatory reaction, cause the usual suppurative response, or occasionally produce granulomas.

Predisposition

- neutropenia

  • acute leukemias
  • post-chemotherapy