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MPO

MIM.606989 17q23.1

Wednesday 23 November 2005

Myeloperoxidase is a lysosomal hemoprotein located in the azurophilic granules of polymorphonuclear (PMN) leukocytes and monocytes.

Pathology

- germline mutations in complete myeloperoxydase deficiency (MPO deficiency) (MIM.254600)

- polymorphism in Alzheimer disease susceptibility