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inositol lipids

Monday 15 September 2003

Phosphoinositide 3-kinases (PI3Ks) generate specific inositol lipids implicated in the regulation of cell growth, proliferation, survival, differentiation, and cytoskeletal changes.

One of the best characterized targets of PI3K lipids are the protein kinases B (PKBs) or AKTs (AKT1 and AKT2). AKT2 (MIM.164731) is the isoform of AKT 1 and is enriched in insulin-responsive tissues and has been implicated in the metabolic actions of the hormone.

See also

- PIK3s (PIK3CA, PIK3CB, PIK3CD, PIK3CG)
- AKTs (AKT1 and AKT2)