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t(11;14)(q13;q32)

Wednesday 2 November 2005

AGCOH

Tumors

- B-cell lymphomas

  • mantle cell lymphoma
  • B-prolymphocytic leukaemia
  • splenic lymphoma with villous lymphocytes
  • chronic lymphocytic leukaemia
  • multiple myeloma
  • plasma cell leukaemia

Genes involved

- CCND1 (BCL1) coding for cyclin-D1 at 11q13
- IGH at 14q32

Links

- AGCOH

References

- Combined molecular diagnosis of B-cell lymphomas with t(11;14)(q13;q32) or t(14;18)(q32;q21) using multiplex- and long distance inverse-polymerase chain reaction. Vieira L, Martinho A, Antunes O, Silva E, Ambrósio AP, Geraldes MC, Nascimento R, Silva C, Pereira JM, Júnior EC, Jordan P. Diagn Mol Pathol. 2008 Jun;17(2):73-81. PMID: 18382373