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Home > G. Tumoral pathology > Molecular pathology of tumors > Genetic anomalies > Cancer cytogenetics > Tumoral trisomies > trisomy 7

trisomy 7

Wednesday 2 November 2005


- papillary renal cell carcinoma
- Lymphomas

  • Burkitt lymphoma

- osseous chondrosarcoma (11793371)
- astrocytomas
- multiforme gliobastoma

Non-tumoral cells

- synovial cells
- nonneoplastic epithelial kidney cells (7835096)

Driver genes



- Eklund E, Broberg K, Westergren-Thorsson G, Bjardahlen A, Hedlund M, Malmstrom A. Proteoglycan production in disomic and trisomy 7-carrying human synovial cells. Matrix Biol. 2002 Jun;21(4):325-35.
PMID: 12128070 [PubMed - indexed for MEDLINE]

- Dahlen A, Broberg K, Domanski HA, Toksvig-Larsen S, Lindstrand A, Mandahl N, Mertens F. Analysis of the distribution and frequency of trisomy 7 in vivo in synovia from patients with osteoarthritis and pigmented villonodular synovitis. Cancer Genet Cytogenet. 2001 Nov;131(1):19-24. PMID: 11734313

- Broberg K, Toksvig-Larsen S, Lindstrand A, Mertens F. Trisomy 7 accumulates with age in solid tumors and non-neoplastic synovia. Genes Chromosomes Cancer. 2001 Mar;30(3):310-5. PMID: 11170291

- Broberg K, Hoglund M, Lindstrand A, Toksvig-Larsen S, Mandahl N, Mertens F. Polyclonal expansion of cells with trisomy 7 in synovia from patients with osteoarthritis. Cytogenet Cell Genet. 1998;83(1-2):30-4. PMID: 9925917

- Bardi G, Johansson B, Pandis N, Heim S, Mandahl N, Andren-Sandberg A, Hagerstrand I, Mitelman F. Trisomy 7 in short-term cultures of colorectal adenocarcinomas. Genes Chromosomes Cancer. 1991 Mar;3(2):149-52. PMID: 2069912

- Berrozpe G, Miro R, Caballin MR, Salvador J, Egozcue J. Trisomy 7 may be a primary change in noninvasive transitional cell carcinoma of the bladder. Cancer Genet Cytogenet. 1990 Nov 1;50(1):9-14. PMID: 2253193

- Limon J, Mrozek K, Heim S, Elfving P, Nedoszytko B, Babinska M, Mandahl N, Lundgren R, Mitelman F. On the significance of trisomy 7 and sex chromosome loss in renal cell carcinoma. Cancer Genet Cytogenet. 1990 Oct 15;49(2):259-63. PMID: 2208062