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complex tumoral karyotypes

Tuesday 11 October 2005

Epithelial tumors commonly show complex and variable karyotypes that obscure the identification of general patterns of the karyotypic evolution.


- epithelial tumors

  • head and neck carcinomas
  • renal cell carcinomas
  • bladder cancer
  • breast cancer
  • colorectal cancer
  • ovarian cancer
  • lung cancer
  • malignant melanoma
  • Wilms tumor

See also

- common patterns of karyotypic evolution.
- hypodiploid pathway
- hyperdiploid pathway
- karyotypic entropy


- Hoglund M, Frigyesi A, Sall T, Gisselsson D, Mitelman F. Statistical behavior of complex cancer karyotypes. Genes Chromosomes Cancer. 2005 Apr;42(4):327-41. PMID: 15645488

- Hoglund M, Gisselsson D, Hansen GB, Mitelman F. Wilms tumors develop through two distinct karyotypic pathways. Cancer Genet Cytogenet. 2004 Apr 1;150(1):9-15. PMID: 15041217