giant cell angiofibroma
Tuesday 11 October 2005
Giant cell angiofibroma seems most often to arise in the head and neck region (predominantly orbit) of adults and which, with the passage of time.
It may well prove to be a variant of solitary fibrous tumour characterized by prominent multinucleate giant cells and lipofibromatosis.
It is a rare tumour occurring predominantly in the hands or feet of infants and young children.
it shows a high rate of local recurrence and consists of a complex admixture of mature adipose tissue and a highly cellular, often primitive-looking fibroblastic component arranged in a septal distribution.
Giant cell angiofibroma of the oral cavity: A case report and review of the literature. de Andrade CR, Lopes MA, de Almeida OP, León JE, Mistro F, Kignel S. Med Oral Patol Oral Cir Bucal. 2008 Sep 1;13(9):E540-3. PMID: 18758395
The evolving classification of soft tissue tumours: an update based on the new WHO classification. Fletcher CD. Histopathology. 2006 Jan;48(1):3-12. PMID: 16359532