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progressive multifocal leukoencephalopathy
Thursday 6 October 2005
The only human disease caused by an infection with the human JC polyomavirus (JCV) is progressive multifocal leukoencephalopathy (PML) characterized by a lytic infection of oligodendrocytes with consecutive demyelination.
Etiology
HIV infection genetic immunodeficiencies
See also
papovavirus polyomaviruses
- JC polyomavirus
- BK polyomavirus
References
Koralnik IJ. New insights into progressive multifocal leukoencephalopathy. Curr Opin Neurol. 2004 Jun;17(3):365-70. PMID: #15167073#
Hair LS, Nuovo G, Powers JM, Sisti MB, Britton CB, Miller JR. Progressive multifocal leukoencephalopathy in patients with human immunodeficiency virus. Hum Pathol. 1992 Jun;23(6):663-7. PMID: #1592389#
