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autosomal microsatellites

Friday 30 September 2005

Fact

- The microsatellite allelic diversity and the number of unique alleles were highest in sub-Saharan Africans. (14533184)

- Neighbor-joining trees based on genetic distances and principal component analyses separated populations from different continents, and are consistent with an African origin for modern humans. (14533184)

- With biparentally transmitted markers, the microsatellite tree also shows that the San are the first branch of the human tree before the branch leading to all other Africans. (14533184)

- No evidence of a genetic relationship has been shown among the Basques and the Hunzo Burusho. (14533184)

- Genetic relationships, as ascertained by these microsatellites, are dictated primarily by geographic proximity rather than by remote linguistic origin, as assesed by Mantel test. (14533184)

See also

- allelic frequencies
- tri-autosomal microsatellites
- tetra-autosomal microsatellites
- phylogenetic studies
- Basques
- Hunza Burusho

References

- Ayub Q, Mansoor A, Ismail M, Khaliq S, Mohyuddin A, Hameed A, Mazhar K, Rehman S, Siddiqi S, Papaioannou M, Piazza A, Cavalli-Sforza LL, Mehdi SQ. Reconstruction of human evolutionary tree using polymorphic autosomal microsatellites. Am J Phys Anthropol. 2003 Nov;122(3):259-68. PMID: 14533184