Wednesday 28 September 2005
The DdeI(10,394)AluI(10,397)(++) haplotype predated the Indo-European invasion and probably the split between proto-Indians and proto-Orientals. Its frequency cline well reflects the major influence of Indo-Europeans in the north and in the center of India. (#8808610#)
The demographic history of India was examined by comparing mtDNA sequences obtained from members of three culturally divergent Indian subpopulations (endogamous caste groups). (#7717409#)
- No clear separation into three genetically distinct groups along caste lines.
- Comparison of pairwise nucleotide difference distributions, however, did indicate a difference in growth patterns between two of the castes.
- The Brahmin population appears to have undergone either a rapid expansion or steady growth.
- The low-ranking Mukri caste, however, may have either maintained a roughly constant population size or undergone multiple bottlenecks during that period.
- Comparison of the Indian sequences to those obtained from other populations, using a tree, revealed that the Indian sequences, along with all other non-African samples, form a starlike cluster.
- This cluster may represent a major expansion, possibly originating in southern Asia, taking place at some point after modern humans initially left Africa.
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