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clenched hand

Tuesday 6 September 2005

Definition: The index overlaps a clenched fist formed by the other digits. The proximal interphalangeal articulation of the index is flexed and ulnarly deviated. The thumb is adducted. This attitude is constant during the examination and is strongly suggestive of trisomy 18.

Etiology

- trisomy 18
- FADS (fetal akinesia deformation sequence)

Differential diagnosis

- Clenched hand must be differentiated from fixed attitudes observed in akinesia-hypokinesia syndromes and from a normal temporary closed fist.