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12q14 region - Humpath.com - Human pathology

Home > B. Cellular pathology > Chromosomes > Chromosomal regions > 12q14 region

12q14 region

Monday 13 June 2005

Cytogentics

- translocations in tumors

  • 12q14 and 7p12
  • 12q14 and 8q22
  • 12q14 and 11q23
  • 12q14 and 12p11
  • 12q14 and 14q31
  • 12q14 and 20q11

- amplification in tumors with genic overexpression

  • targer genes: CDK4

Molecular biology

  • HMGA2 fusion genes
  • truncated HMGA2 isoforms

Tumors

- lipomas