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acute pancreatitis

Wednesday 11 May 2005

Synopsis

- complications

  • peripancreatic free fluid collections
  • extrapancreatic spread of acute pancreatitis
  • infected or noninfected pseudocysts
  • pancreatic abscess
  • complex cystic structure with internal debris/septations and echogenic gas bubbles
  • vascular pseudoaneurysm
  • acute hemorrhage
  • venous thrombosis
  • associated gastric varices

Etiology

- obstructive (obstruction or overdistension of the pancreatic duct)

  • gallstones migration (60-80% of cases)
  • biliary malformations or pancreatic malformations
    • pancreas divisum
    • choledochocele
  • ampullary tumors or pancreatic tumors

- toxic

  • exposure to ethanol (alcohol abuse)
  • other toxics
  • drugs
    • azathioprine
    • glucocorticoids (#15235881#, #12911675#, #12843925#, #12722354#)
    • cyclosporin-A
    • furosemide
    • calcium chloride

- infectious

  • mumps
  • cytomegalovirus (CMV)
  • Epstein-Barr virus
  • varicella
  • rubeola
  • group B coxsackievirus
  • enterovirus
  • enteric cytopathic human orphan virus (ECHO virus)

- dysimmunity

  • systemic erythematosus lupus (#14582568#, #12949035#)
  • overlap syndrome of systemic sclerosis and systemic lupus erythematosus (#16767557#)
  • polyarteritis nodosa (#15693106#)
  • autoimmune pancreatitis (hyper-IgG4 syndrome) (#15549456#)
  • ulcerative colitis (#15235881#, #12911675#)

- metabolic

  • hypertriglyceridemia
  • hypercalcemia
  • MELAS with mitochondrial DNA tRNALeu(UUR) gene mutations (#8891562#)
  • Reye syndrome

- trauma

  • blunt trauma to the abdomen
  • iatrogenic trauma
    • postoperative trauma
    • endoscopic retrograde cholangiopancreatography

- vascular abnormalities

  • atherosclerotic emboli
  • hypoperfusion
  • vasculitis

- cystic fibrosis
- unknown cause (10-25%)
- orthotopic liver allograft (#9523868#)

  • emergency liver allograft
  • extensive peripancreatic dissection
  • pancreatic surgical trauma
  • infectious peritonitis

According to age

- pediatric acute pancreatitis

Portfolio

  • Acute necrotizing pancreatitis
  • Acute necrotizing pancreatitis
  • Acute necrotizing pancreatitis
  • Acute necrotizing pancreatitis
  • Acute necrotizing pancreatitis
  • Acute necrotizing pancreatitis