constrictive bronchiolitis

Constrictive bronchiolitis designates inflammation and fibrosis occurring predominantly in the walls and contiguous tissues of membranous and respiratory bronchioles, with resultant narrowing of their lumens.

Synopsis

 concentric bronchiolar fibrosis

Types

 active constrictive bronchiolitis
 inactive constrictive bronchiolitis

Etiology

 healed pulmonary infections

• respiratory syncitial virus (VRS)
• cytomegalovirus
• adenovirus
• influenza virus
• parainfluenza virus
• varicella
• mycoplasma

 organ allograft

• -* pulmonary allograft rejection (pulmonary transplantation)
• heart-lung allograft
• bone marrow allograft

 fumes

• nitrogen oxide

 toxins (inhaled or ingested)

• Sauropus androgynous

 drugs

• penicillamine
• lomustine

 dysimmunity (systemic connective tissue disease)

• rheumatoid arthritis
• pemphigus vulgaris
• inflammatory bowel diseases (IBDs)

 drugs

 unknown cause (idiopathic constrictive bronchiolitis)

See also

 bronchiolitis

• obliterative bronchiolitis (bronchiolitis obliterans)
  • bronchiolitis obliterans syndrome (BOS)

 pulmonary lesions

• bronchiolar lesions
• peribronchiolar lesions
• bronchiolocentric lesions

References

 Schlesinger C, Veeraraghavan S, Koss MN. Constructive (obliterative) bronchiolitis. Curr Opin Pulm Med. 1998 Sep;4(5):288-93. PMID: 10813204

 Schlesinger C, Meyer CA, Veeraraghavan S, Koss MN. Constrictive (obliterative) bronchiolitis: diagnosis, etiology, and a critical review of the literature. Ann Diagn Pathol. 1998 Oct;2(5):321-34. PMID: 9845757