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inguinal glandular inclusions

Tuesday 22 March 2005

Glandular inclusions in inguinal hernia sacs have resemblance to the epididymis or vas deferens. Most of hernia sac inclusions, we thought were Mullerian duct-derived structures.

Types

- CD10- vas deferens-like
- CD10 +/- epididymis-like
- CD10- Mullerian-like
- external diameter <1 mm

Differential diagnosis

- transected vas deferens

  • CD10+
  • external diameter > 1 mm

Immunochemistry

- inguinal hernia sac glandular inclusions are CD10-

  • CD10+ in Wolffian-type epithelium
  • CD10- in Mullerian-type epithelium

References

- Cerilli LA, Sotelo-Avila C, Mills SE. Glandular inclusions in inguinal hernia sacs: morphologic and immunohistochemical distinction from epididymis and vas deferens. Am J Surg Pathol. 2003 Apr;27(4):469-76. PMID: #12657931#

- Gomez-Roman JJ, Mayorga M, Mira C, Buelta L, Fernandez F, Val-Bernal JF. Glandular inclusions in inguinal hernia sacs: a clinicopathological study of six cases. Pediatr Pathol. 1994 Nov-Dec;14(6):1043-9. PMID: #855006#

- Walker AN, Mills SE. Glandular inclusions in inguinal hernial sacs and spermatic cords. Mullerian-like remnants confused with functional reproductive structures. Am J Clin Pathol. 1984 Jul;82(1):85-9. PMID: #6741877#

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