hematopoietic stem cells
Sunday 13 July 2003
Haematopoietic stem cells (HSCs) are multipotent, self-renewing progenitors that generate all mature blood cells.
HSC function is tightly controlled to maintain haematopoietic homeostasis, and this regulation relies on specialized cells and factors that constitute the haematopoietic ’niche’, or microenvironment.
Chute JP. Stem cell homing. Curr Opin Hematol. 2006 Nov;13(6):399-406. PMID: 17053451