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Home > E. Pathology by systems > Reproductive system > Fetus and annexes > Embryo and fetus > urethral obstruction sequence

urethral obstruction sequence

Wednesday 23 February 2005


- megacystis

  • prune belly sequence

- bilateral megaureteres
- bilateral hydronephrosis
- bilateral ostructive renal dysplasia
- oligohydramnios sequence

Case records

- Case record #10038
- Case record #11598: Megacystis in urethral obstruction sequence (UOS) with prune belly syndrome


- Berry C. Patterns of congenital lower urinary tract obstructive uropathy.
Pediatr Dev Pathol. 2003 Mar-Apr;6(2):202-3; author reply 203. PMID: 12574913

- Volmar KE, Fritsch MK, Perlman EJ, Hutchins GM. Patterns of congenital lower urinary tract obstructive uropathy: relation to abnormal prostate and bladder development and the prune belly syndrome. Pediatr Dev Pathol. 2001 Sep-Oct;4(5):467-72. PMID: 11779049

- Poucell-Hatton S, Huang M, Bannykh S, Benirschke K, Masliah E. Fetal obstructive uropathy: patterns of renal pathology. Pediatr Dev Pathol. 2000 May-Jun;3(3):223-31. PMID: 10742409

- Fryns JP, Vandenberghe K, Deschrijver D. Early urethral obstruction sequence and unbalanced translocation with terminal 10p duplication/1p deficiency. Genet Couns. 1997;8(4):349-50. PMID: 9457507

- van Buggenhout G, Cooreman G, Thienpont L, Fryns JP. Early urethral obstruction sequence and trisomy of the long arm of chromosome 1. Ann Genet. 1995;38(2):106-7. PMID: 7486825

- Bierkens AF, Feitz WF, Nijhuis JG, de Wildt MJ, Flos MS, de Vries JD. Early urethral obstruction sequence: a lethal entity? Fetal Diagn Ther. 1996 Mar-Apr;11(2):137-45. PMID: 8838771

- Perez-Aytes A, Graham JM, Hersh JH, Hoyme HE, Aleck K, Carey JC. Urethral obstruction sequence and lower limb deficiency: evidence for the vascular disruption hypothesis. J Pediatr. 1993 Sep;123(3):398-405. PMID: 8355115