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renal oncocytosis

Monday 21 February 2005

renal oncocytomatosis

Definition: Renal oncocytosis is a rare disorder in which numerous oncocytic nodules develop in the kidney. Renal oncocytosis is a precursor lesion of renal oncocytoma and chromophobe renal cell carcinoma.

The renal cell neoplasms of oncocytosis seem to have distinct morphologic, immunohistochemical, and cytogenetic profiles and likely are a distinct entity, not closely related to oncocytoma or chromophobe renal cell carcinoma. (20305535)


- Renal oncocytosis: a clinicopathological and cytogenetic study of 42 tumours occurring in 11 patients. 2016.

- Renal cell neoplasms of oncocytosis have distinct morphologic, immunohistochemical, and cytogenetic profiles. Gobbo S, Eble JN, Delahunt B, Grignon DJ, Samaratunga H, Martignoni G, Zhang S, Wang M, Brunelli M, Cossu-Rocca P, Cheng L. Am J Surg Pathol. 2010 May;34(5):620-6. PMID: 20305535

- Renal oncocytosis. Nagashima Y, Mitsuya T, Shioi KI, Noguchi S, Kishida T, Hamano A, Ohgo Y, Tsuura Y, Ogawa T, Aoki I, Yao M. Pathol Int. 2005 Apr;55(4):210-5. PMID: 15826248

- Al-Saleem T, Cairns P, Dulaimi EA, Feder M, Testa JR, Uzzo RG. The genetics of renal oncocytosis: a possible model for neoplastic progression. Cancer Genet Cytogenet. 2004 Jul 1;152(1):23-8. PMID: 15193438