Wednesday 9 February 2005
Definition: Periportal hepatocytic necrosis is the necrosis of hepatocytes localized around the portal vein. It is usually associated with ingested toxins.
Periportal necrosis rather than the more usual perivenular necrosis is a feature in some patients with hepatitis A.
- ferrous sulfate intoxication
- yellow phosphorus toxicity
- acetic acid ingestion
The diagnostic significance of periportal hepatic necrosis and inflammation (Link)