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Home > A. Molecular pathology > PLEC1


MIM.601282 8q24

Monday 31 January 2005

Plectin-1 (PLEC1) is one of the largest polypeptides known, was originally identified as a major component of intermediate filament preparations obtained from cultured cells. It is a 500-kD intermediate filament binding protein and may provide mechanical strength to cells and tissues by acting as a cross linking element of the cytoskeleton.


- germline mutations of PLEC1 in

See also