Monday 31 January 2005
Collagen XVII, or BP180, is a type II transmembrane protein that is a structural component of hemidesmosomes, multiprotein complexes that mediate the adhesion of epidermal keratinocytes to the underlying basement membrane.
target for auto-antibody in bullous pemphigoid
germline mutations in
- generalized atrophic benign epidermolysis bullosa (MIM.226650)
Hirako Y, Owaribe K. Hemidesmosomes and their unique transmembrane protein BP180. Microsc Res Tech. 1998 Nov 1;43(3):207-17. PMID: 9840798