Tuesday 18 January 2005
Four genes have recently been proposed as candidates for dyslexia:
dyslexia susceptibility 1 candidate 1 (DYX1C1)
roundabout Drosophila homolog 1 (ROBO1)
doublecortin domain-containing protein 2 (DCDC2)
Each gene is implicated in global brain-development processes such as neural migration and axonal guidance, with the exception of DYX1C1, the function of which is still unknown.
McGrath LM, Smith SD, Pennington BF. Breakthroughs in the search for dyslexia candidate genes. Trends Mol Med. 2006 Jul;12(7):333-41. PMID: 16781891