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pseudomembranous colitis

Monday 10 January 2005

Defintion : The pseudomembranous colitis inflammatory pattern is associated with infections primarily caused by Clostridium difficile and less frequently by other bacteria (E. coli, Shigella).

A similar pattern may be caused by ischemia, certain drugs and radiation injury.

The diffuse distribution of the lesions favor an infectious or drug induced etiology. The localized distribution of the lesions favor an ischemic etiology.


- Pseudomembranous Colitis, Colectomy Specimen by Ed Euthman


- Clostridium difficile

  • antibiotherapy


- possible presence of signet ring cells

See also

- colitis