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situs solitus

Thursday 6 January 2005

Definition: Situs solity is the normality of assymetry or laterality.

Pathology

- heterotaxy (situs anomalies, laterality disorders)

  • situs ambiguus (incomplete situs inversus)
  • situs inversus totalis
  • isomerisms
    • left isomerism
    • right isomerism

- syndromal heterotaxy

References

- Peeters H, Devriendt K. Human laterality disorders. Eur J Med Genet. 2006 Sep-Oct;49(5):349-62. Epub 2006 Jan 3. PMID: 16461029

- Aylsworth AS. Clinical aspects of defects in the determination of laterality. Am J Med Genet. 2001 Jul 15;101(4):345-55. PMID: 11471158

- Casey B. Two rights make a wrong: human left-right malformations. Hum Mol Genet. 1998;7(10):1565-71. PMID: 9735377

- Ibanez-Tallon I, Heintz N, Omran H. To beat or not to beat : roles of cilia in development and disease. Hum Mol Genet. 2003 Apr 2 ;12(Suppl 1) :R27-35. PMID : 12668594

- El Zein L, Omran H, Bouvagnet P. Lateralization defects and ciliary dyskinesia : lessons from algae. Trends Genet. 2003 Mar ;19(3):162-7. PMID : 12615011

See also

- situs anomalies

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