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viral cytopathic effects

Monday 13 December 2004

viral cytopathic changes; viral cytopathogenic effects

Types

- viral inclusions

  • nuclear viral inclusions
    • cytomegalic inclusions (CMV inclusion)
  • cytoplasmic viral inclusions

- multinucleation
- dog ear proerythroblasts : parvovirus B19
- koilocytosis : HPV Human papillomavirus
- decoy cells : BK virus in immunocompromised / transplant patients
- demyelination with enlarged oligodendrocytes : JC Virus
- ground glass hepatocytes : hepatitis B virus HBV
- multinucleated cells with intranuclear Cowdry inclusions : HSV Herpesvirus simplex
- Downey cells / atypical lymphocytes : EBV
- cells with increased size and cytoplasmic granular and nuclear inclusions : CMV
- Kapsoi sarcoma : HHV8
- Guarneri bodies : variola / small pox
- cytoplasmic eosinophilic inclusions in umbilcated skin lesions / epidermal crateriform anomalies : molluscum contagiosum
- blast cells with flower shaped nuclei : HTLV
- Warthin-Finkedley cells : measles
- Negri bodies

Examples

- viral cytopathic changes in CMV gastritis

- viral inclusions
- herpes esophagitis

References

- Pranav Patwardhan

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