Home > E. Pathology by systems > Digestive system > Liver > massive hepatic necrosis
massive hepatic necrosis
Wednesday 8 December 2004
Massive and submassive hepatic necrosis are the histopathological counterpart of fulminant hepatic failure.
Etiology
infections
- acute viral hepatitis (60 to 75%)
intoxications (drugs and toxins) (20%)
- drug-induced hepatic necrosis
- toxin-induced hepatic necrosis
severe hepatic ischemia hepatic metabolic diseases
- Wilson disease
- hereditary tyrosinemia
- galactosemia
- hereditary fructose intolerance
congenital hemochromatosis acute auto-immune hepatitis
