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nuchal-type fibroma

Tuesday 23 November 2004

Nuchal-type fibroma (NTF ) is a paucicellular, CD34+ fibrous tumor with fat entrapment, which may occur in both nuchal and extranuchal locations and in association with Gardner syndrome.

Nuchal-type fibroma most often occurs in the posterior neck or upper trunk of younger adult males.

It may be associated with diabetes mellitus

It is characterized by a poorly marginated proliferation of hypocellular collagenous tissue showing entrapment of mature adipose tissue and numerous small nerves.

Predisposition

- APC-associated Gardner syndrome

Associations

- desmoid fibromatosis (#11395565#)
- dermatofibrosarcoma protuberans (sporadic) (#14675287#)

References

- Allen PW. Nuchal-type fibroma appearance in a desmoid fibromatosis. Am J Surg Pathol. 2001 Jun;25(6):828-9. PMID: #11395565#

- Dawes LC, La Hei ER, Tobias V, Kern I, Stening W. Nuchal fibroma should be recognized as a new extracolonic manifestation of Gardner-variant familial adenomatous polyposis. Aust N Z J Surg. 2000 Nov;70(11):824-6. PMID: #11147449#

- Michal M, Fetsch JF, Hes O, Miettinen M. Nuchal-type fibroma: a clinicopathologic study of 52 cases. Cancer. 1999 Jan 1;85(1):156-63. PMID: #9921988#